Evidence map›Paper›PMID 34452160›Full record

ReviewPharmaceutics2021

Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair.

Eliana B Souto, Cristiana M P Yoshida, Gislaine R Leonardi, Amanda Cano, Elena Sanchez-Lopez, Aleksandra Zielinska, César Viseras, Patricia Severino, Classius F da Silva, Raquel de M Barbosa

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Differentiation of Plant and Animal-Derived Cholesterol Using irm-Magnetic resonance in chemistry : MRC · 2026
    Article
  3. Dermocosmetic Potential ofAntioxidants (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Study on Differences of Metabolites among DifferentJournal of fungi (Basel, Switzerland) · 2024
    Article
  6. Recreating Human Skin In Vitro: Should the Microbiota Be Taken into Account?International journal of molecular sciences · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eliana B SoutoCEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Cristiana M P YoshidaFaculty of Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, Diadema, São Paulo 09913-030, Brazil.
Gislaine R LeonardiFaculty of Pharmaceutical Sciences, State University of Campinas, Rua Cândido Portinari, 200-Cidade Universitária, Campinas 13083-871, Brazil.
Amanda CanoDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0001-9567-4283
Elena Sanchez-LopezDepartment of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-2571-108X
Aleksandra ZielinskaCEB-Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-2603-1377
César ViserasDepartment of Pharmacy and Pharmaceutical Technology, School of Pharmacy, University of Granada, Campus of Cartuja s/n, 18071 Granada, Spain.ORCID 0000-0002-2219-3566
Patricia SeverinoInstitute of Technology and Research (ITP), Av. Murilo Dantas, 300, Aracaju 49010-390, Brazil.ORCID 0000-0001-6527-6612
Classius F da SilvaFaculty of Pharmaceutical Sciences, Federal University of São Paulo, Rua São Nicolau, 210, Diadema, São Paulo 09913-030, Brazil.ORCID 0000-0001-9937-5598
Raquel de M BarbosaLaboratory of Drug Development, Department of Pharmacy, School of Pharmacy, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil.ORCID 0000-0003-3798-5512

Funding

This research was funded by the Portuguese Science and Technology Foundation (FCT/MCT) and European Funds (PRODER/COMPETE), co-financed by FEDER, under the Partnership Agreement PT2020. UIDB/04469/2020
6 · The paper itself

Abstract

The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.

Indexed as

biopolymerslipid-polymeric filmslipidsskin repair

Identifiers

PMID34452160
PMCPMC8398446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.