ReviewPharmaceutics2021
Encapsulation of Active Pharmaceutical Ingredients in Lipid Micro/Nanoparticles for Oral Administration by Spray-Cooling.
Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Microencapsulation Strategies in Veterinary Medicine: Overcoming Gastrointestinal Barriers in Monogastric and Ruminant Species.Pharmaceutics · 2026Review
- Natural Macromolecules as Building Blocks for Microcapsule Formation in Drug Delivery.Pharmaceutics · 2026Review
- Microencapsulation of Probiotics for Enhanced Stability and Health Benefits in Dairy Functional Foods: A Focus on Pasta Filata Cheese.Pharmaceutics · 2025Review
- Probiotic applications of bifidobacteria in poultry: administration methods and microencapsulation techniques.Microbiome research reports · 2025Review
- Plant bioactive compounds: extraction, biological activities, immunological, nutritional aspects, food application, and human health benefits-A comprehensive review.Frontiers in nutrition · 2025Review
- From Extraction to Stabilization: Employing a 2Foods (Basel, Switzerland) · 2024Article
- Enteral Route Nanomedicine for Cancer Therapy.International journal of nanomedicine · 2024Review
- Application of Encapsulation Strategies for Probiotics: From Individual Loading to Co-Encapsulation.Microorganisms · 2023Review
- Mairá-Potato (Molecules (Basel, Switzerland) · 2023Review
- Efficient strategies for controlled release of nanoencapsulated phytohormones to improve plant stress tolerance.Plant methods · 2023Review
- Flavour encapsulation: A comparative analysis of relevant techniques, physiochemical characterisation, stability, and food applications.Frontiers in nutrition · 2023Review
- Lipid-based oral formulation in capsules to improve the delivery of poorly water-soluble drugs.Frontiers in drug delivery · 2023Review
- Solid Lipid Microparticles by Spray Congealing of Water/Oil Emulsion: An Effective/Versatile Loading Strategy for a Highly Soluble Drug.Pharmaceutics · 2022Article
- Fabrication of Encapsulated Gemini Surfactants.Molecules (Basel, Switzerland) · 2022Article
- Nutraceutical Concepts and Dextrin-Based Delivery Systems.International journal of molecular sciences · 2022Review
- Microencapsulation by spray chilling in the food industry: Opportunities, challenges, and innovations.Trends in food science & technology · 2022Review
- How could nanobiotechnology improve treatment outcomes of anti-TNF-α therapy in inflammatory bowel disease? Current knowledge, future directions.Journal of nanobiotechnology · 2021Review
- Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair.Pharmaceutics · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Nanoencapsulation via spray cooling (also known as spray chilling and spray congealing) has been used with the aim to improve the functionality, solubility, and protection of drugs; as well as to reduce hygroscopicity; to modify taste and odor to enable oral administration; and many times to achieve a controlled release profile. It is a relatively simple technology, it does not require the use of low-cost solvents (mostly associated to toxicological risk), and it can be applied for lipid raw materials as excipients of oral pharmaceutical formulations. The objective of this work was to revise and discuss the advances of spray cooling technology, with a greater emphasis on the development of lipid micro/nanoparticles to the load of active pharmaceutical ingredients for oral administration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.