Evidence map›Paper›PMID 34452140›Full record

ArticlePharmaceutics2021

In Vitro Effect of Photodynamic Therapy with Different Lights and Combined or Uncombined with Chlorhexidine on

Vanesa Pérez-Laguna, Yolanda Barrena-López, Yolanda Gilaberte, Antonio Rezusta

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Vanesa Pérez-LagunaMax Planck Institute for Evolutionary Biology, 24306 Plön, Germany.ORCID 0000-0002-5331-7170
Yolanda Barrena-LópezDepartment of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, 50001 Zaragoza, Spain.
Yolanda GilaberteAragon Health Research Institute (IIS Aragón), 50009 Zaragoza, Spain.
Antonio RezustaDepartment of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, 50001 Zaragoza, Spain.
Universidad de Zaragoza · ESHospital Universitario Miguel Servet · ESMax Planck Institute for Evolutionary Biology · DE

Funding

Aragón Government, Spain B10_17R Infectious Diseases of Difficult Diagnosis and Treatment research group and B18_17D Dermatology and Photobiology research groupSpanish Ministerio de Economía y Competitividad grant CTQ2013-48767-C3-2-R
6 · The paper itself

Abstract

Candidiasis is very common and complicated to treat in some cases due to increased resistance to antifungals. Antimicrobial photodynamic therapy (aPDT) is a promising alternative treatment. It is based on the principle that light of a specific wavelength activates a photosensitizer molecule resulting in the generation of reactive oxygen species that are able to kill pathogens. The aim here is the in vitro photoinactivation of three strains of

Indexed as

antimicrobial photodynamic therapyC. albicanscandidiasismethylene blue

Identifiers

PMID34452140
PMCPMC8398142
OpenAlexW3189230701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.