Evidence map›Paper›PMID 34452131›Full record

ArticlePharmaceutics2021

Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of

Ruiying Li, Floriane Laurent, Alistair Taverner, Julia Mackay, Paul A De Bank, Randall J Mrsny

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Interactions between Nanoparticles and Intestine.International journal of molecular sciences · 2022
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruiying LiDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
Floriane LaurentDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
Alistair TavernerDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.ORCID 0000-0002-2507-8694
Julia MackayDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
Paul A De BankDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
Randall J MrsnyDepartment of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK.
University of Bath · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The low permeability of nanoparticles (NPs) across the intestinal epithelium remains a major challenge for their application of delivering macromolecular therapeutic agents via the oral route. Previous studies have demonstrated the epithelial transcytosis capacity of a non-toxic version of

Indexed as

in vivo modelnanoparticleoral protein deliverytranscytosis

Identifiers

PMID34452131
PMCPMC8402016
OpenAlexW3184698240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.