Evidence map›Paper›PMID 34452123›Full record

ArticlePharmaceutics2021

The Influence of Formulation Components and Environmental Humidity on Spray-Dried Phage Powders for Treatment of Respiratory Infections Caused by

Wei Yan, Ruide He, Xiaojiao Tang, Bin Tian, Yannan Liu, Yigang Tong, Kenneth K W To, Sharon S Y Leung

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Phage as a prospective arsenal against superbugs.Molecular biology reports · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Wei YanSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Shatin, NewTerritories, Hong Kong, China.
Ruide HeLivzon Pharmaceutical Group Co., Ltd., Zhu Hai 519090, China.
Xiaojiao TangLivzon Pharmaceutical Group Co., Ltd., Zhu Hai 519090, China.
Bin TianDepartment of Pharmaceutical Sciences, School of Food and Biological Engineering, Shanxi University of Science and Technology, Weiyang University Park, Xi'an 710021, China.
Yannan LiuEmergency Medicine Clinical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100069, China.
Yigang TongBeijing Advanced Innovation Center for Soft Matter Science and Engineering (BAIC-SM), College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.
Kenneth K W ToSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Shatin, NewTerritories, Hong Kong, China.
Sharon S Y LeungSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Shatin, NewTerritories, Hong Kong, China.ORCID 0000-0002-0194-7058
Chinese University of Hong Kong · HKChina National Pharmaceutical Group Corporation (China) · CNBeijing University of Chemical Technology · CNCapital Medical University · CNShanxi University · CN

Funding

Research Grants Council, University Grants Committee 24300619
6 · The paper itself

Abstract

The feasibility of using respirable bacteriophage (phage) powder to treat lung infections has been demonstrated in animal models and clinical studies. This work investigated the influence of formulation compositions and excipient concentrations on the aerosol performance and storage stability of phage powder. An anti-

Indexed as

aerosol performancebacterial lung infectionsenvironmental humidityinhalationphage therapyspray drying

Identifiers

PMID34452123
PMCPMC8401170
OpenAlexW3183237398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.