Evidence map›Paper›PMID 34451937›Full record

ReviewVaccines2021

Next-Generation Bioinformatics Approaches and Resources for Coronavirus Vaccine Discovery and Development-A Perspective Review.

Rahul Chatterjee, Mrinmoy Ghosh, Susrita Sahoo, Santwana Padhi, Namrata Misra, Visakha Raina, Mrutyunjay Suar, Young-Ok Son

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. COVID-19 Vaccines: Computational tools and Development.Informatics in medicine unlocked · 2023
    Review
  7. Review
  8. Review
  9. Article
  10. Health economic burden of COVID-19 in Saudi Arabia.Frontiers in public health · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rahul ChatterjeeSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar 751 024, India.
Mrinmoy GhoshKIIT-Technology Business Incubator (KIIT-TBI), Bhubaneswar 751 024, India.ORCID 0000-0001-6817-622X
Susrita SahooSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar 751 024, India.
Santwana PadhiKIIT-Technology Business Incubator (KIIT-TBI), Bhubaneswar 751 024, India.
Namrata MisraSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar 751 024, India.
Visakha RainaSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar 751 024, India.
Mrutyunjay SuarSchool of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar 751 024, India.
Young-Ok SonDepartment of Animal Biotechnology, Faculty of Biotechnology, Jeju National University, Jeju 63243, Korea.ORCID 0000-0003-0154-4061
KIIT University · INJeju National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To fight this pandemic, which has caused a massive death toll around the globe, researchers are putting efforts into developing an effective vaccine against the pathogen. As genome sequencing projects for several coronavirus strains have been completed, a detailed investigation of the functions of the proteins and their 3D structures has gained increasing attention. These high throughput data are a valuable resource for accelerating the emerging field of immuno-informatics, which is primarily aimed toward the identification of potential antigenic epitopes in viral proteins that can be targeted for the development of a vaccine construct eliciting a high immune response. Bioinformatics platforms and various computational tools and databases are also essential for the identification of promising vaccine targets making the best use of genomic resources, for further experimental validation. The present review focuses on the various stages of the vaccine development process and the vaccines available for COVID-19. Additionally, recent advances in genomic platforms and publicly available bioinformatics resources in coronavirus vaccine discovery together with related immunoinformatics databases and advances in technology are discussed.

Indexed as

bioinformatics resourcescoronavirusepitopeimmunoinformaticsvaccine

Identifiers

PMID34451937
PMCPMC8402397
OpenAlexW3185647651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.