Evidence map›Paper›PMID 34451864›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

Synthesis, Biological Evaluation, and In Silico Modeling of

Ghada Bouz, Sarah Bouz, Ondřej Janďourek, Klára Konečná, Pavel Bárta, Jarmila Vinšová, Martin Doležal, Jan Zitko

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ghada BouzFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0003-2024-5788
Sarah BouzFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.
Ondřej JanďourekFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0003-4633-2062
Klára KonečnáFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0001-5670-7767
Pavel BártaFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0001-5445-5658
Jarmila VinšováFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.
Martin DoležalFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0003-1558-6625
Jan ZitkoFaculty of Pharmacy in Hradec Králové, Charles University, 50005 Hradec Králové, Czech Republic.ORCID 0000-0003-0104-9925
Charles University · CZ

Funding

European Food Safety Authority CZ.02.1.01/0.0/0.0/16_019/0000841Grantová Agentura České Republiky 20-19638Y
6 · The paper itself

Abstract

Despite the established treatment regimens, tuberculosis remains an alarming threat to public health according to WHO. Novel agents are needed to overcome the increasing rate of resistance and perhaps achieve eradication. As part of our long-term research on pyrazine derived compounds, we prepared a series of their ortho fused derivatives,

Indexed as

antimycobacterialcytotoxicitymolecular dockingMycobacterium tuberculosispyrazinamidequinoxalinetuberculosis

Identifiers

PMID34451864
PMCPMC8399443
OpenAlexW3187117823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.