Evidence map›Paper›PMID 34451491›Full record

ArticlePathogens (Basel, Switzerland)2021

Establishment of a Rhesus Macaque Model for Scrub Typhus Transmission: Pilot Study to Evaluate the Minimal

Piyada Linsuwanon, Sirima Wongwairot, Nutthanun Auysawasdi, Taweesak Monkanna, Allen L Richards, Surachai Leepitakrat, Piyanate Sunyakumthorn, Rawiwan Im-Erbsin, Katie Poole-Smith, Patrick McCardle

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. First Report of 'Veterinary sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Piyada LinsuwanonDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Sirima WongwairotDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Nutthanun AuysawasdiDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Taweesak MonkannaDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Allen L RichardsDepartment of Preventive Medicine and Biostatistics, Uniformed Services University of Health Sciences, Bethesda, MD 20814, USA.ORCID 0000-0002-1065-429X
Surachai LeepitakratDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Piyanate SunyakumthornDepartment of Veterinary Medicine, USAMD-AFRIMS, Bangkok 10330, Thailand.
Rawiwan Im-ErbsinDepartment of Veterinary Medicine, USAMD-AFRIMS, Bangkok 10330, Thailand.
Katie Poole-SmithDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.
Patrick McCardleDepartment of Entomology, USAMD-AFRIMS, Bangkok 10330, Thailand.ORCID 0000-0001-6322-7892
Armed Forces Research Institute of Medical Science · THUniformed Services University of the Health Sciences · US

Funding

Military Infectious Diseases Research Program (MIDRP)-Rickettsial Disease
6 · The paper itself

Abstract

Recently, an intradermal inoculation of the rhesus macaque model of scrub typhus has been characterized at our institution. The current project was to establish a rhesus macaque model of scrub typhus using the naturally infected chigger challenge method that faithfully mimics the natural route of pathogen transmission to fully understand the host-pathogen-vector interactions influencing pathogen transmission. Unlike the needle-based inoculation route,

Indexed as

chigger transmissionscrub typhusscrub typhus disease modeltransmission time

Identifiers

PMID34451491
PMCPMC8402083
OpenAlexW3195263887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.