Evidence map›Paper›PMID 34451398›Full record

ArticlePathogens (Basel, Switzerland)2021

Presence of SARS-CoV-2 in a Cornea Transplant.

Myriem Otmani Idrissi, Jean-Pierre Baudoin, Anne-Line Chateau, Sarah Aherfi, Marielle Bedotto-Buffet, Alain Latil, Hubert Lepidi, Jacques Chiaroni, Christophe Picard, Jean-Louis Mege and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. The neurobiology of SARS-CoV-2 infection.Nature reviews. Neuroscience · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Myriem Otmani IdrissiAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.ORCID 0000-0001-5950-0059
Jean-Pierre BaudoinAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.
Anne-Line ChateauEFS Provence Alpes Côte d'Azur Corse, 13005 Marseille, France.
Sarah AherfiAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.
Marielle Bedotto-BuffetAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.
Alain LatilCH d'Antibes-Juan Les Pins, 06160 Antibes, France.
Hubert LepidiAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.
Jacques ChiaroniEFS Provence Alpes Côte d'Azur Corse, 13005 Marseille, France.
Christophe PicardEFS Provence Alpes Côte d'Azur Corse, 13005 Marseille, France.
Jean-Louis MegeAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.
Bernard La ScolaAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.ORCID 0000-0001-8006-7704
Soraya MezouarAix-Marseille University, MEPHI, IRD, APHM, 13005 Marseille, France.ORCID 0000-0002-2285-7051
Aix-Marseille Université · FRCentre National de la Recherche Scientifique · FRCentre Procédés, Energies Renouvelables et Systèmes Energétiques · FRDélégation Régionale Provence-Alpes-Côte d’Azur et Corse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe SARS-CoV-2 pandemic has impacted tissue transplantation procedures since conjunctivas were found to be associated with coronavirus infection. Here, we investigated infection of a cornea graft from a COVID-19-positive donor.

methodsIn order to evaluate the presence of SARS-CoV-2 in the cornea graft we first carried out a qRT-PCR and then we investigated the presence of SARS-CoV-2 by fluorescence and electron microscopy.

conclusionsAlthough the cornea graft was found to be negative by qRT-PCR, we were able to show the presence of SARS-CoV-2 in corneal cells expressing the SARS-CoV-2 receptor, ACE2. Taken together, our findings may have important implications for the use of corneal tissue in graft indications and open the debate on SARS-CoV-2 transmissibility.

Indexed as

corneaCOVID-19SARS-CoV-2

Identifiers

PMID34451398
PMCPMC8401771
OpenAlexW3183863591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.