Evidence map›Paper›PMID 34451392›Full record

ArticlePathogens (Basel, Switzerland)2021

Evaluation of Critical Quality Attributes of a Pentavalent (A, C, Y, W, X) Meningococcal Conjugate Vaccine for Global Use.

Barbara Bolgiano, Eilís Moran, Nicola J Beresford, Fang Gao, Rory Care, Trusha Desai, Ida Karin Nordgren, Timothy R Rudd, Ian M Feavers, Prashant Bore and 16 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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  4. ModelingInfectious Disease Modelling · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 4 countries.

Barbara BolgianoNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.ORCID 0000-0002-9428-3536
Eilís MoranNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Nicola J BeresfordNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Fang GaoNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Rory CareNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Trusha DesaiNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Ida Karin NordgrenNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Timothy R RuddNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.ORCID 0000-0003-4434-0333
Ian M FeaversNational Institute for Biological Standards and Control, South Mimms, Potters Bar EN6 3QG, UK.
Prashant BoreSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Sushil PatniSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Vinay GavadeSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Asha MallyaSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Sameer KaleSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Pankaj SharmaSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Sunil K GoelSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Sunil GairolaSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Suhas HattarkiSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Nikhil AvalaskarSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Annamraju D SarmaSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Marc LaForceSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Neil RavenscroftDepartment of Chemistry, University of Cape Town, Rondebosch, Cape Town 7701, South Africa.
Lakshmi KhandkeCenter for Vaccine Innovation and Access, PATH, Seattle, WA 98121, USA.
Mark R AldersonCenter for Vaccine Innovation and Access, PATH, Seattle, WA 98121, USA.ORCID 0000-0002-0697-6149
Rajeev M DhereSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Sambhaji S PisalSerum Institute of India Pvt. Ltd., Hadapsar, Pune 411028, India.
Serum Institute of India (India) · INNational Institute for Biological Standards and Control · GBProgram for Appropriate Technology in Health · USUniversity of Cape Town · ZA

Funding

Foreign, Commonwealth & Development Office PATH MVPP 300341-108
6 · The paper itself

Abstract

Towards achieving the goal of eliminating epidemic outbreaks of meningococcal disease in the African meningitis belt, a pentavalent glycoconjugate vaccine (NmCV-5) has been developed to protect against

Indexed as

acetylationadjuvantchromatographyglycoconjugatesimmunogenicitymeningitisNeisseria meningitidisnuclear magnetic resonance spectroscopypolysaccharideserum bactericidal

Identifiers

PMID34451392
PMCPMC8400332
OpenAlexW3184566360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.