Evidence map›Paper›PMID 34451338›Full record

ArticlePolymers2021

Hybrid Hosts Based on Sodium Alginate and Porous Clay Heterostructures for Drug Encapsulation.

Anda Ionelia Voicu Mihai, Sorina Alexandra Gȃrea, Eugeniu Vasile, Adi Ghebaur, Horia Iovu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anda Ionelia Voicu MihaiFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Sorina Alexandra GȃreaFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Eugeniu VasileDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Material Science, University Politehnica of Bucharest, 1-7 Polizu, 011061 Bucharest, Romania.
Adi GhebaurFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Horia IovuFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROAcademy of Romanian Scientists · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, some hybrid materials based on sodium alginate (NaAlg) and porous clay heterostructures (PCHs) were investigated as new hosts for 5-Fluorouracil (5-FU) encapsulation. The hybrid hosts were prepared by ionotropic gelation technique using different concentrations of PCHs (1, 3, and 10 wt%) in order to identify the optimal parameters for encapsulation and drug release. The obtained hybrid materials were characterized using FTIR Spectrometry, thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and UV-Vis spectrometry to investigate the interactions of the raw materials involved in the preparation of hybrid hosts, the influence of PCHs concentrations on drug encapsulation efficiency and drug release profile. All the results show that the synthesized hybrid materials were able to load a high amount of 5-FU, the encapsulation efficiency and the release profile being influenced by the concentrations of PCHs.

Indexed as

5-Fluorouracildrughybridsporous clay heterostructuressodium alginate

Identifiers

PMID34451338
PMCPMC8400238
OpenAlexW3193327467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.