ArticleEuropean journal of dentistry2022
Systematic Review on White Spot Lesions Treatments.
Article in European journal of dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Effect of Self-Assembling Peptide on White Spot Lesions in Orthodontic Patients: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2026Pooled it
- Can Orthodontic Adhesive Systems Inhibit the Formation and Development of White Spot Lesions During Fixed Orthodontic Treatment? A Systematic Review.The journal of adhesive dentistry · 2024Pooled it
- Comparative assessment of four treatments for post orthodontic white spot lesions over a 24-month period: a randomized controlled clinical trial.BMC oral health · 2026Trial
- Remineralising efficacy of bioactive glass and casein phosphopeptide amorphous calcium phosphate in white spot lesions or early enamel caries: A systematic review of randomised controlled trials.The Japanese dental science review · 2026Review
- Methodological Heterogeneity in Profilometric Assessment of Experimentally Demineralized Enamel as a Model of White Spot Lesions: A Systematic Review.Journal of functional biomaterials · 2026Review
- Modulating the Optical Properties of Initial Caries Lesions Through Low-Viscosity Resin Infiltration: A Spectrophotometric Evaluation.Journal of functional biomaterials · 2026Article
- Bridging the Gap Between Knowledge and Practice: Contemporary Preventive Strategies in Modern Dental Care-A Cross-Sectional Survey of Practicing Dentists.Journal of clinical medicine · 2026Article
- Comparative clinical evaluation of Icon resin infiltration and Vanish XT varnish for managing white spot lesions: a randomized controlled trial.The Saudi dental journal · 2026Article
- Prevalence of white spot lesions in children and adolescents across Northern, Central and Southern Italy: a multicenter cross-sectional study.Frontiers in oral health · 2026Article
- Effect of Ginger Extracts in Remineralization of White Spot Lesions: A Systematic Review and Meta-analysis.International journal of clinical pediatric dentistry · 2025Article
- Time-Effect Comparative Evaluation of Three Remineralizing Agents on Artificial Enamel Lesions: A SEM-EDX In Vitro Study.Journal of clinical medicine · 2025Article
- Evaluation of enamel remineralization potential and anticariogenic efficacy of polydopamine coated biogenic amorphous calcium phosphate.Clinical oral investigations · 2025Article
- Color Change and Color Stability of White Spot Lesions Treated with Resin Infiltration, Microabrasion, or Nano-Hydroxyapatite Remineralization: An In Vitro Study.Dentistry journal · 2025Article
- Whitening Efficiency of Papain and Bromelain Gels in Removing Dental Stains.Gels (Basel, Switzerland) · 2025Article
- Systematic Review and Meta-Analysis of Remineralizing Agents: Outcomes on White Spot Lesions.Bioengineering (Basel, Switzerland) · 2025Review
- Efficacy of an Experimental CPP-ACP and Fluoride Toothpaste in Prevention of Enamel Demineralization: An In Vitro Study on Bovine Enamel.International journal of dentistry · 2025Article
- Article
- A Comprehensive Review of Treatment Plans for Marginal Enamel Fractures in Anterior Teeth.Biomimetics (Basel, Switzerland) · 2024Review
- The Staining Susceptibility and Surface Roughness of Teeth Restored by Microabrasion and Resin Infiltration: An In Vitro Study.Polymers · 2024Article
- A Review of White Spot Lesions: Development and Treatment with Resin Infiltration.Dentistry journal · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The difference in refractive index between the healthy enamel and the demineralized area generates a lesion with a milky white opaque appearance, clearly distinguishable from the surrounding healthy enamel. The aim of this systematic review was to evaluate if the infiltration technique is the most efficient treatment to resolve a white spot lesion when compared with remineralization and microabrasion techniques. The Population/Intervention/Comparison/Outcome question investigated: "in enamel WS lesion, the infiltration treatment compared to remineralization or microabrasion treatments is more or less effective in the camouflage effect?." The research was performed on electronic databases, including Ovid MEDLINE, PubMed, and web of science. The search was conducted up to April 1, 2020. The scientific search engines produced 324 results. Only 14 were screened after screening. Based on the articles analyzed in this systematic review, the resin infiltration technique seems to be the most effective and predictable treatment for the aesthetic resolution of WSLs.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.