Evidence map›Paper›PMID 34450675›Full record

ArticleAmerican journal of perinatology2023

Early Vital Sign Differences in Very Low Birth Weight Infants with Severe Intraventricular Hemorrhage.

Santina A Zanelli, Maryam Abubakar, Robert Andris, Kavita Patwardhan, Karen D Fairchild, Zachary A Vesoulis

Open access · greenAbstract read
In one paragraph

Article in American journal of perinatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Santina A ZanelliDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia.ORCID 0000-0003-1210-7043
Maryam AbubakarDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia.
Robert AndrisDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia.
Kavita PatwardhanDepartment of Pediatrics, Division of Newborn Medicine, Washington University, St. Louis, Missouri.
Karen D FairchildDepartment of Pediatrics, University of Virginia, Charlottesville, Virginia.
Zachary A VesoulisDepartment of Pediatrics, Division of Newborn Medicine, Washington University, St. Louis, Missouri.
University of Virginia · USWashington University in St. Louis · US

Funding

Predictive Informatics Monitoring in the Neonatal Intensive Care UnitR01HD072071 · NICHD · UNIVERSITY OF VIRGINIA · PI KAREN D FAIRCHILD, Brynne Archer Sullivan · 2014 to 2026
$7.6M
Integrated physiomarker, biomarker and clinical predictive analytics for early warning of sepsis and necrotizing enterocolitis in very low birth weight infants.K23HD097254 · NICHD · UNIVERSITY OF VIRGINIA · PI SULLIVAN, BRYNNE ARCHER · 2019 to 2023
$897k
Racial Disparities in Preterm Brain Injury Are Driven by Differences in Cerebral AutoregulationK23NS111086 · NINDS · WASHINGTON UNIVERSITY · PI VESOULIS, ZACHARY ANDREW · 2019 to 2022
$736k
NICHD NIH HHS K23 HD097254NICHD NIH HHS R01 HD072071NINDS NIH HHS K23 NS111086
6 · The paper itself

Abstract

objectiveSevere intraventricular hemorrhage (sIVH, grades 3 and 4) is a serious complication for very low birth weight (VLBW) infants and is often clinically silent requiring screening cranial ultrasound (cUS) for detection. Abnormal vital sign (VS) patterns might serve as biomarkers to identify risk or occurrence of sIVH. STUDY

designThis retrospective study was conducted in VLBW infants admitted to two level-IV neonatal intensive care units (NICUs) between January 2009 and December 2018. Inclusion criteria were: birth weight <1.5 kg and gestational age (GA) <32 weeks, at least 12 hours of systemic oxygen saturation from pulse oximetry (SpO

resultsA total of 639 infants (mean: 27 weeks' gestation) were included (567 no IVH, 34 early sIVH, and 37 late sIVH). In the first 48 hours, those with sIVH had significantly higher HR compared with those with no IVH. Infants with sIVH also had lower mean SpO

conclusionVLBW infants who develop sIVH demonstrate VS differences with significantly lower SpO KEY POINTS: · A higher HR in the first 48 hours is seen in infants with severe IVH.. · Infants with sIVH have lower blood pressure in the first 48 hours.. · Infants with sIVH have more oxygen desaturations in the first 48 hours..

Indexed as

Infant, PrematureInfant, Premature, DiseasesBirth WeightCerebral HemorrhageGestational AgeHumansInfantInfant, NewbornInfant, Very Low Birth WeightRetrospective StudiesRisk FactorsVital Signs

Identifiers

PMID34450675
PMCPMC9188354
OpenAlexW3193850128

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.