Evidence map›Paper›PMID 34450654›Full record

ArticleJournal of molecular cell biology2022

Syntelin inhibits triple-negative breast cancer cell proliferation and metastasis.

McKay Mullen, Fengrui Yang, Jun Cao, Yang Cao, Xu Liu, Gee Young Lee, Tao Li, William Yao, Zhihong Yang, Jiahai Zhang and 9 more

Open access · goldAbstract readLetter
In one paragraph

Article in Journal of molecular cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Akt-elicited phosphorylation of Acapin steers cell migration.Journal of molecular cell biology · 2025
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

McKay MullenMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Fengrui YangMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Jun CaoMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Yang CaoDepartment of Hepatobiliary Surgery, Xijing Hospital, Xi'an 710032, China.
Xu LiuMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Gee Young LeeKeck Center for Oganoids Plasticity, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Tao LiMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
William YaoBUCM-USTC Collaborative Center for Parietal Cell Research, Beijing University of Chinese Medicine, Beijing 100029, China.
Zhihong YangMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Jiahai ZhangMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Kela JohnsonKeck Center for Oganoids Plasticity, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Felix AikhionbareKeck Center for Oganoids Plasticity, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Yong ChenDepartment of Hepatobiliary Surgery, Xijing Hospital, Xi'an 710032, China.
Xinjiao GaoMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Dongmei WangMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
Xia DingBUCM-USTC Collaborative Center for Parietal Cell Research, Beijing University of Chinese Medicine, Beijing 100029, China.
Hadiyah-Nicole GreenKeck Center for Oganoids Plasticity, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Xing LiuMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.ORCID 0000-0002-7480-5085
Xuebiao YaoMOE Key Laboratory for Cellular Dynamics, Anhui Key Laboratory for Chemical Biology, CAS Center for Excellence in Molecular Cell Science, University of Science and Technology of China, Hefei 230027, China.
University of Science and Technology of China · CNXijing Hospital · CNBeijing University of Chinese Medicine · CNMorehouse School of Medicine · US

Funding

Morehouse School of Medicine Center of Excellence Research Endowment ProgramS21MD000101 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI MONTGOMERY-RICE, VALERIE C. · 2001 to 2015
$74.3M
Function of ACAP4 in CCL18-stimulated breast cancer metastasisR01CA164133 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI YAO, XUEBIAO · 2012 to 2016
$1.4M
NCI NIH HHS R01 CA164133NIMHD NIH HHS S21 MD000101
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Triple Negative Breast NeoplasmsCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHeterocyclic Compounds, 3-RingHumansNeoplasm MetastasisThioglycolatesHeterocyclic Compounds, 3-RingsyntelinThioglycolates

Identifiers

PMID34450654
PMCPMC8782585
OpenAlexW3195192780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.