Evidence map›Paper›PMID 34450590›Full record

ArticleJournal of neurosurgery. Spine2021

Smartphone GPS signatures of patients undergoing spine surgery correlate with mobility and current gold standard outcome measures.

Alessandro Boaro, Jeffrey Leung, Harrison T Reeder, Francesca Siddi, Elisabetta Mezzalira, Gang Liu, Rania A Mekary, Yi Lu, Michael W Groff, Jukka-Pekka Onnela and 1 more

Abstract read
In one paragraph

Article in Journal of neurosurgery. Spine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Beyond one-time PROMs: high-frequency single-item mobile ePROM tracking of postoperative recovery in spine surgery-a prospective feasibility study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandro Boaro1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.
Jeffrey Leung1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.
Harrison T Reeder2Department of Biostatistics, Harvard T.H. Chan School of Public Health.
Francesca Siddi1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.
Elisabetta Mezzalira1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.
Gang Liu2Department of Biostatistics, Harvard T.H. Chan School of Public Health.
Rania A Mekary1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.
Yi Lu5Department of Neurosurgery, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts.
Michael W Groff5Department of Neurosurgery, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts.
Jukka-Pekka Onnela2Department of Biostatistics, Harvard T.H. Chan School of Public Health.
Timothy R Smith1Computational Neuroscience Outcomes Center, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School.

Funding

Methods for High-Dimensional Statistical Inference and Individualized Risk Prediction under Semi-Competing RisksF31HD102159 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI REEDER, HARRISON · 2020 to 2021
$74k
NICHD NIH HHS F31 HD102159
6 · The paper itself

Abstract

objectivePatient-reported outcome measures (PROMs) are currently the gold standard to evaluate patient physical performance and ability to recover after spine surgery. However, PROMs have significant limitations due to the qualitative and subjective nature of the information reported as well as the impossibility of using this method in a continuous manner. The smartphone global positioning system (GPS) can be used to provide continuous, quantitative, and objective information on patient mobility. The aim of this study was to use daily mobility features derived from the smartphone GPS to characterize the perioperative period of patients undergoing spine surgery and to compare these objective measurements to PROMs, the current gold standard.

methodsEight daily mobility features were derived from smartphone GPS data in a population of 39 patients undergoing spine surgery for a period of 2 months starting 3weeks before surgery. In parallel, three different PROMs for pain (visual analog scale [VAS]), disability (Oswestry Disability Index [ODI]) and functional status (Patient-Reported Outcomes Measurement Information System [PROMIS]) were serially measured. Segmented linear regression analysis was used to assess trends before and after surgery. The Student paired t-test was used to compare pre- and postoperative PROM scores. Pearson's correlation was calculated between the daily average of each GPS-based mobility feature and the daily average of each PROM score during the recovery period.

resultsSmartphone GPS features provided data documenting a reduction in mobility during the immediate postoperative period, followed by a progressive and steady increase with a return to baseline mobility values 1 month after surgery. PROMs measuring pain, physical performance, and disability were significantly different 1 month after surgery compared to the 2 immediate preoperative weeks. The GPS-based features presented moderate to strong linear correlation with pain VAS and PROMIS physical score during the recovery period (Pearson r > 0.7), whereas the ODI and PROMIS mental scores presented a weak correlation (Pearson r approximately 0.4).

conclusionsSmartphone-derived GPS features were shown to accurately characterize perioperative mobility trends in patients undergoing surgery for spine-related diseases. Features related to time (rather than distance) were better at describing patient physical and performance status. Smartphone GPS has the potential to be used for the development of accurate, noninvasive and personalized tools for patient mobility monitoring after surgery.

Indexed as

SmartphoneSpinal DiseasesGeographic Information SystemsHumansMobility LimitationOutcome Assessment, Health CarePainPatient Reported Outcome Measuresdigital phenotypingGPSPROMssmartphonespine surgery

Identifiers

PMID34450590
PMCPMC9012532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.