Evidence map›Paper›PMID 34450569›Full record

ArticleHearing research2021

Analyses of the Tympanic Membrane Impulse Response Measured with High-Speed Holography.

H Tang, P Psota, J J Rosowski, C Furlong, J T Cheng

Abstract read
In one paragraph

Article in Hearing research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Systematic Review and Meta-Analysis of Audiometric Parameters for Assistive Hearing Technology for Adults and Children With Tympanic Membrane Perforation.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025
    Pooled it
  2. Article
  3. Article
  4. The Transmission of Sound to the Cochlea in Normal and Pathological Human Middle Ears.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Review
  5. Article
  6. Contemporary Mechanics of Conductive Hearing Loss.Operative techniques in otolaryngology--head and neck surgery · 2024
    Article
  7. Article
  8. Article
  9. Mammalian middle ear mechanics: A review.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H TangCenter for Holographic Studies and Laser Micro-mechaTronics (CHSLT), Worcester Polytechnic Institute, Worcester, MA United States; Mechanical Engineering Department, Worcester Polytechnic Institute, Worcester, MA United States; Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA United States. Electronic address: htang3@wpi.edu.
P PsotaFaculty of Mechatronics, Informatics and Interdisciplinary Studies, Technical University of Liberec, Liberec, Czech Republic.
J J RosowskiEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA United States; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, United States.
C FurlongCenter for Holographic Studies and Laser Micro-mechaTronics (CHSLT), Worcester Polytechnic Institute, Worcester, MA United States; Mechanical Engineering Department, Worcester Polytechnic Institute, Worcester, MA United States; Eaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA United States; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, United States.
J T ChengEaton-Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, MA United States; Department of Otolaryngology-Head and Neck Surgery, Harvard Medical School, Boston, MA, United States.

Funding

Middle Ear Nonlinearity in High Intensity Sound: Impact on Hearing Damage and ProtectionR01DC016079 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Jeffrey Tao Cheng · 2017 to 2026
$4.1M
NIDCD NIH HHS R01 DC016079
6 · The paper itself

Abstract

The Tympanic Membrane (TM) transforms acoustic energy to ossicular vibration. The shape and the displacement of the TM play an important role in this process. We developed a High-speed Digital Holography (HDH) system to measure the shape and transient displacements of the TM induced by acoustic clicks. The displacements were further normalized by the measured shape to derive surface normal displacements at over 100,000 points on the TM surface. Frequency and impulse response analyses were performed at each TM point, which enable us to describe 2D surface maps of four new TM mechanical parameters. From frequency domain analyses, we describe the (i) dominant frequencies of the displacement per sound pressure based on Frequency Response Function (FRF) at each surface point. From time domain analyses, we describe the (ii) rising time, (iii) exponential decay time, and the (iv) root-mean-square (rms) displacement of the TM based on Impulse Response Function (IRF) at each surface point. The resultant 2D maps show that a majority of the TM surface has a dominant frequency of around 1.5 kHz. The rising times suggest that much of the TM surface is set into motion within 50 µs of an impulsive stimulus. The maps of the exponential decay time of the IRF illustrate spatial variations in damping, the least known TM mechanical property. The damping ratios at locations with varied dominant frequencies are quantified and compared.

Indexed as

HolographyTympanic MembraneAcoustic StimulationEar, MiddleSoundVibrationFrequency response functionHigh-speed digital holographyImpulse response functionMechanical propertiesMiddle earTympanic membrane

Identifiers

PMID34450569
PMCPMC8484071

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.