Evidence map›Paper›PMID 34450547›Full record

ArticleEnvironment international2021

Primary aromatic amines in indoor dust from 10 countries and associated human exposure.

Sridhar Chinthakindi, Kurunthachalam Kannan

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 36 citations in OpenAlex.

  1. Unexpected Exposure Risks to Emerging Aromatic Amine Antioxidants andEnvironment & health (Washington, D.C.) · 2024
    Article
  2. Tracking Aromatic Amines from Sources to Surface Waters.Environmental science & technology letters · 2024
    Review
  3. Article
  4. Occurrence of 1,3-Diphenylguanidine, 1,3-Di-Environmental science & technology · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sridhar ChinthakindiDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, United States.
Kurunthachalam KannanDepartment of Pediatrics and Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, United States. Electronic address: Kurunthachalam.kannan@nyulangone.org.
New York University · US

Funding

Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR)U2CES026542 · NIEHS · WADSWORTH CENTER · PI KANNAN, KURUNTHACHALAM, KANNAN, KURUNTHACHALAM · 2015 to 2025
$15.6M
NIEHS NIH HHS U2C ES026542
6 · The paper itself

Abstract

Although primary aromatic amines (AAs) are widely used in consumer products, little is known about their occurrence in indoor dust. A liquid chromatography - tandem mass spectrometry (LC-MS/MS) method was applied for the determination of 29 AAs and two tobacco smoke markers (nicotine and cotinine) in 256 house dust samples collected from 10 countries. Of the 29 AAs analyzed, p-anisidine, o-anisidine, 2,6-dimethylaniline (2,6-DMA), p-cresidine (p-CD), p-toluidine (p-TD), 4,4'-methylenedianiline (4,4'-MDA), ortho/meta-toluidine (o/m-TD), 4-chloroaniline (4-CA), 2,4-diaminotoluene (2,4-DAT), aniline, and 2-naphthylamine (2-NA) as well as nicotine and cotinine, were found prevalent in house dust samples. Sum median concentrations of AAs and tobacco smoke markers varied from 29.6 to 576 ng/g (overall median: 200 ng/g) and 10.8 to 2920 ng/g (415 ng/g), respectively. Among AAs, aniline was the abundant contaminant, found at median concentrations ranging from 19.6 ng/g (Colombia) to 334 ng/g (South Korea). Nicotine was detected in all indoor samples at median concentrations ranging from 9.92 ng/g (Colombia) to 2790 ng/g (India) ng/g. Concentrations of AAs in indoor dust were significantly correlated with those of nicotine. Estimated daily intake (EDI) of select AAs through the ingestion of house dust was in the range of 0.019-3.03 ng/kg-bw/day, which was five orders of magnitude below the tolerance limits.

Indexed as

Air Pollution, IndoorDustAminesChromatography, LiquidEnvironmental ExposureHumansSmokeTandem Mass SpectrometryAminesDustSmokeAnilineAromatic aminesIndoor dustLC-MS/MSNicotine

Identifiers

PMID34450547
PMCPMC8490295
OpenAlexW3195420346

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.