Evidence map›Paper›PMID 34450183›Full record

ArticleExperimental neurology2021

Painful diabetic neuropathy leads to functional Ca

Tal Hoffmann, Katrin Kistner, Sonja L J Joksimovic, Slobodan M Todorovic, Peter W Reeh, Susanne K Sauer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Regulatory Action of Calcium and Calcium Channels in Pain Pathways.International journal of biological sciences · 2025
    Review
  3. Review
  4. Review
  5. Voltage-dependent CaPflugers Archiv : European journal of physiology · 2022
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Tal HoffmannInstitute for Physiology and Pathophysiology, University of Erlangen-Nuremberg, Universitaetsstrasse 17, 91054 Erlangen, Germany.
Katrin KistnerInstitute for Physiology and Pathophysiology, University of Erlangen-Nuremberg, Universitaetsstrasse 17, 91054 Erlangen, Germany.
Sonja L J JoksimovicDepartment of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.
Slobodan M TodorovicDepartment of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO 80045, USA.
Peter W ReehInstitute for Physiology and Pathophysiology, University of Erlangen-Nuremberg, Universitaetsstrasse 17, 91054 Erlangen, Germany.
Susanne K SauerInstitute for Physiology and Pathophysiology, University of Erlangen-Nuremberg, Universitaetsstrasse 17, 91054 Erlangen, Germany. Electronic address: susanne.sauer@fau.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Colorado Anschutz Medical Campus · US

Funding

Molecular mechanisms of glycosylation of Cav3.2 channels in pain pathwayR01NS091353 · NINDS · UNIVERSITY OF COLORADO DENVER · PI JEVTOVIC-TODOROVIC, VESNA, TODOROVIC, SLOBODAN M. · 2016 to 2020
$1.8M
NINDS NIH HHS R01 NS091353
6 · The paper itself

Abstract

Painful diabetic neuropathy occurs in approximately 20% of diabetic patients with underlying pathomechanisms not fully understood. We evaluated the contribution of the Ca

Indexed as

AnimalsCalcium Channels, T-TypeDiabetes Mellitus, ExperimentalDiabetic NeuropathiesFemaleGene ExpressionMaleMiceMice, Inbred C57BLMice, KnockoutNeuralgiaNociceptorsOrgan Culture TechniquesSkinCacna1h protein, mouseCalcium Channels, T-TypeCalcitonin gene-related peptideExcitabilityNeuropathic painNeuropeptide releaseSciatic nerveTTA-P2T-type calcium channel

Identifiers

PMID34450183
PMCPMC8549116
OpenAlexW3194133742

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.