ArticleCurrent biology : CB2021
Drosophila re-zero their path integrator at the center of a fictive food patch.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Article
- Finding a path: local search behavior of Drosophila larvae.The Journal of experimental biology · 2025Article
- Building an Egocentric-to-Allocentric Travelling Direction Transformation Model for Enhanced Navigation in Intelligent Agents.Sensors (Basel, Switzerland) · 2025Article
- Continuous integration of heading and goal directions guides steering.bioRxiv : the preprint server for biology · 2024Article
- Exploration-exploitation trade-off is regulated by metabolic state and taste value inbioRxiv : the preprint server for biology · 2024Article
- Temporal effects of sugar intake on fly local search and honey bee dance behaviour.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024Article
- The conserved RNA-binding protein Imp is required for the specification and function of olfactory navigation circuitry in Drosophila.Current biology : CB · 2024Article
- Emergent spatial goals in an integrative model of the insect central complex.PLoS computational biology · 2023Article
- Tracking Sugar-Elicited Local Searching Behavior in Drosophila.Journal of visualized experiments : JoVE · 2023Article
- Lineages to circuits: the developmental and evolutionary architecture of information channels into the central complex.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Review
- Displacement experiments provide evidence for path integration in Drosophila.The Journal of experimental biology · 2023Article
- The RNA-binding protein, Imp specifies olfactory navigation circuitry and behavior inbioRxiv : the preprint server for biology · 2023Article
- Varieties of visual navigation in insects.Animal cognition · 2023Review
- Connectomics and the neural basis of behaviour.Current opinion in insect science · 2022Review
- Article
- From Photons to Behaviors: Neural Implementations of Visual Behaviors inFrontiers in neuroscience · 2022Review
- Article
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4 authors.
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Abstract
The ability to keep track of one's location in space is a critical behavior for animals navigating to and from a salient location, and its computational basis is now beginning to be unraveled. Here, we tracked flies in a ring-shaped channel as they executed bouts of search triggered by optogenetic activation of sugar receptors. Unlike experiments in open field arenas, which produce highly tortuous search trajectories, our geometrically constrained paradigm enabled us to monitor flies' decisions to move toward or away from the fictive food. Our results suggest that flies use path integration to remember the location of a food site even after it has disappeared, and flies can remember the location of a former food site even after walking around the arena one or more times. To determine the behavioral algorithms underlying Drosophila search, we developed multiple state transition models and found that flies likely accomplish path integration by combining odometry and compass navigation to keep track of their position relative to the fictive food. Our results indicate that whereas flies re-zero their path integrator at food when only one feeding site is present, they adjust their path integrator to a central location between sites when experiencing food at two or more locations. Together, this work provides a simple experimental paradigm and theoretical framework to advance investigations of the neural basis of path integration.
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