Evidence map›Paper›PMID 34449907›Full record

ArticleThe New phytologist2021

Serrate-Associated Protein 1, a splicing-related protein, promotes miRNA biogenesis in Arabidopsis.

Mu Li, Huihui Yu, Kan Liu, Weilong Yang, Bangjun Zhou, Lu Gan, Shengjun Li, Chi Zhang, Bin Yu

Open access · bronzeAbstract read
In one paragraph

Article in The New phytologist, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Artificial miRNAs and target-mimics as potential tools for crop improvement.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. microRNA production inFrontiers in plant science · 2023
    Review
  9. Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Mu LiSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0002-8442-7006
Huihui YuSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0003-2725-1937
Kan LiuSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.
Weilong YangSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.
Bangjun ZhouSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.
Lu GanSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0001-5726-1496
Shengjun LiSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0003-0469-3222
Chi ZhangSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0002-1827-8137
Bin YuSchool of Biological Sciences & Center for Plant Science Innovation, University of Nebraska-Lincoln, Lincoln, NE, 68588-0666, USA.ORCID 0000-0002-4763-177X
University of Nebraska–Lincoln · US

Funding

Understand the function of the MOS4-associated complex in microRNA biogenesisR01GM127414 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI YU, BIN · 2018 to 2022
$1.6M
NIGMS NIH HHS R01 GM127414
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are essential regulators of gene expression in metazoans and plants. In plants, most miRNAs are generated from primary miRNA transcripts (pri-miRNAs), which are processed by the Dicer-like 1 (DCL1) complex along with accessory proteins. Serrate-Associated Protein 1 (SEAP1), a conserved splicing-related protein, has been studied in human and yeast. However, the functions of SEAP1 in plants remain elusive. Lack of SEAP1 results in embryo lethality and knockdown of SEAP1 by an artificial miRNA (amiR

Indexed as

ArabidopsisArabidopsis ProteinsMicroRNAsCell Cycle ProteinsGene Expression Regulation, PlantRNA-Binding ProteinsRNA Processing, Post-TranscriptionalArabidopsis ProteinsCell Cycle ProteinsMicroRNAsRNA-Binding ProteinsArabidopsisDCL1miRNA biogenesisSE and HYL1SEAP1splicing

Identifiers

PMID34449907
PMCPMC8568667
OpenAlexW3195263083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.