ArticlePloS one2021
Linking a European cohort of children born with congenital anomalies to vital statistics and mortality records: A EUROlinkCAT study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Drug Utilization Studies in Pregnant Women for Newly Licensed Medicinal Products: A Contribution from IMI ConcePTION.Journal of pregnancy · 2024Pooled it
- Survival, hospitalisation and surgery in children born with Pierre Robin sequence: a European population-based cohort study.Archives of disease in childhood · 2023Pooled it
- Accuracy of congenital anomaly coding in live birth children recorded in European health care databases, a EUROlinkCAT study.European journal of epidemiology · 2023Pooled it
- Survival of children with rare structural congenital anomalies: a multi-registry cohort study.Orphanet journal of rare diseases · 2022Pooled it
- Mortality amongst European children with congenital anomalies: Associations with socio-economic status in the EUROLINKCAT cohort.PloS one · 2026Observational
- Health-related quality of life at 5 years of age for children born very preterm with congenital anomalies: a multi-national cohort study.Pediatric research · 2025Article
- Recommendations for Improving Surveillance of Congenital Anomalies in Europe Using Healthcare Databases.Paediatric and perinatal epidemiology · 2025Article
- Health outcomes and drug utilisation in children with Noonan syndrome: a European cohort study.Orphanet journal of rare diseases · 2025Article
- Exposure to golimumab during pregnancy: Results from the Company's global safety database.Pharmacology research & perspectives · 2024Article
- The Association of Prenatal Diagnoses with Mortality and Long-Term Morbidity in Children with Specific Isolated Congenital Anomalies: A European Register-Based Cohort Study.Maternal and child health journal · 2024Article
- Hospital care in the first 10 years of life of children with congenital anomalies in six European countries: data from the EUROlinkCAT cohort linkage study.Archives of disease in childhood · 2024Article
- Timing of Cardiac Surgical Interventions and Postoperative Mortality in Children With Severe Congenital Heart Defects Across Europe: Data From the EUROlinkCAT Study.Journal of the American Heart Association · 2023Article
- Causes of death in children with congenital anomalies up to age 10 in eight European countries.BMJ paediatrics open · 2023Article
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- Temporal and geographical variations in survival of children born with congenital anomalies in Europe: A multi-registry cohort study.Paediatric and perinatal epidemiology · 2022Article
- Breastfeeding, pregnancy, medicines, neurodevelopment, and population databases: the information desert.International breastfeeding journal · 2022Review
- COVID-19 in pregnancy-what study designs can we use to assess the risk of congenital anomalies in relation to COVID-19 disease, treatment and vaccination?Paediatric and perinatal epidemiology · 2022Review
- Gastrostomy and congenital anomalies: a European population-based study.BMJ paediatrics open · 2022Article
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Corrections and comments
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Authors and funding
38 authors at 20 institutions in 13 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
EUROCAT is a European network of population-based congenital anomaly (CA) registries. Twenty-one registries agreed to participate in the EUROlinkCAT study to determine if reliable information on the survival of children born with a major CA between 1995 and 2014 can be obtained through linkage to national vital statistics or mortality records. Live birth children with a CA could be linked using personal identifiers to either their national vital statistics (including birth records, death records, hospital records) or to mortality records only, depending on the data available within each region. In total, 18 of 21 registries with data on 192,862 children born with congenital anomalies participated in the study. One registry was unable to get ethical approval to participate and linkage was not possible for two registries due to local reasons. Eleven registries linked to vital statistics and seven registries linked to mortality records only; one of the latter only had identification numbers for 78% of cases, hence it was excluded from further analysis. For registries linking to vital statistics: six linked over 95% of their cases for all years and five were unable to link at least 85% of all live born CA children in the earlier years of the study. No estimate of linkage success could be calculated for registries linking to mortality records. Irrespective of linkage method, deaths that occurred during the first week of life were over three times less likely to be linked compared to deaths occurring after the first week of life. Linkage to vital statistics can provide accurate estimates of survival of children with CAs in some European countries. Bias arises when linkage is not successful, as early neonatal deaths were less likely to be linked. Linkage to mortality records only cannot be recommended, as linkage quality, and hence bias, cannot be assessed.
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