Evidence map›Paper›PMID 34449737›Full record

ArticleTropical medicine and infectious disease2021

The Effect of HBV/HCV in Response to HAART in HIV Patients after 12 Months in Kumba Health District in the South West Region of Cameroon.

Adamu Ndongho Ndifontiayong, Innocent Mbulli Ali, Jean Baptiste Sokoudjou, Jerimiah Mbogwe Ndimumeh, Christopher Bonglavnyuy Tume

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adamu Ndongho NdifontiayongResearch Unit of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon.
Innocent Mbulli AliResearch Unit of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon.ORCID 0000-0002-1112-6376
Jean Baptiste SokoudjouResearch Unit of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon.ORCID 0000-0003-4189-0604
Jerimiah Mbogwe NdimumehResearch Unit of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon.
Christopher Bonglavnyuy TumeResearch Unit of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang, Dschang P.O. Box 67, Cameroon.
Université de Dschang · CMUniversité de Yaoundé I · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B (HBV) and C (HCV) are two among the numerous forms of infections whose clinical degeneration, morbidity-mortality and low immune responsiveness in people living with human immunodeficiency virus (HIV) are highly evident. Co-infection of HIV with HBV and HCV has been associated with reduced survival, increased risk of progression to liver diseases and increased risk of hepatotoxicity associated with antiretroviral therapy (ARV). We carried out biochemical, immunological, virological and clinical analysis of hepatitis B and C positive HIV patients as well as some HIV positive individuals receiving antiretroviral therapy in Kumba Health District to evaluate the immune response to the ARV therapy and identified risk factors associated with the treatment outcomes. A total of 52 HIV patients, 36 HIV/HBV and 12 HIV/HCV patients were involved in this study. We performed CD4 counts, viral load test, analyzed ALAT/ASAT, albumin, bilirubin, and creatinine and measured the weights of HIV patients, HIV/HBV and HIV/HCV enrolled for not more than one year in Kumba Health District. The results were analyzed to evaluate the immune response and possible risk factors associated with the treatment outcomes. The mean increase in weight in participants of all groups over 12 months (17.12 kg) was greater than the mean increase in CD4 (8.92 cell/mm

Indexed as

co-infectionhepatitis B and ChepatotoxicityHIVimmune responseKumba

Identifiers

PMID34449737
PMCPMC8396274
OpenAlexW3192791858

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.