Evidence map›Paper›PMID 34449689›Full record

ReviewNeurology international2021

Paliperidone to Treat Psychotic Disorders.

Hormazd D Minwalla, Peter Wrzesinski, Allison Desforges, Joshua Caskey, Brittany Wagner, Patrick Ingraffia, James C Patterson, Amber N Edinoff, Adam M Kaye, Alan D Kaye and 2 more

Abstract readReview
In one paragraph

Review in Neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hormazd D MinwallaDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71103, USA.
Peter WrzesinskiDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71103, USA.
Allison DesforgesSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.ORCID 0000-0001-8362-0640
Joshua CaskeySchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
Brittany WagnerSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
Patrick IngraffiaSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
James C PattersonDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71103, USA.
Amber N EdinoffDepartment of Psychiatry and Behavioral Medicine, Louisiana State University Health Sciences Center, 1501 Kings Hwy, Shreveport, LA 71103, USA.ORCID 0000-0001-7436-6206
Adam M KayeDepartment of Pharmacy Practice, Thomas J. Long School of Pharmacy and Health Sciences, University of the Pacific, Stockton, CA 95211, USA.ORCID 0000-0002-7224-3322
Alan D KayeDepartment of Anesthesiology, Louisiana State University, Shreveport, LA 71103, USA.ORCID 0000-0003-2464-0187
Omar ViswanathDepartment of Anesthesiology, Louisiana State University, Shreveport, LA 71103, USA.
Ivan UritsDepartment of Anesthesiology, Louisiana State University, Shreveport, LA 71103, USA.ORCID 0000-0002-3652-6085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis is a comprehensive review of the literature regarding the use of paliperidone in the treatment of schizophrenia and schizoaffective disorder. It covers the background and presentation of schizophrenia and schizoaffective disorder, as well as the mechanism of action and drug information for paliperidone. It covers the existing evidence of the use of paliperidone for the treatment of schizophrenia and schizoaffective disorder. RECENT

findingsSchizophrenia and schizoaffective disorder lead to significant cognitive impairment. It is thought that dopamine dysregulation is the culprit for the positive symptoms of schizophrenia and schizoaffective disorder. Similar to other second-generation antipsychotics, paliperidone has affinity for dopamine D SUMMARY: Schizophrenia and schizoaffective disorder have a large impact on cognitive impairment, positive symptoms and negative symptoms. Patients with either of these mental illnesses suffer from impairments in everyday life. Paliperidone has been shown to reduce symptoms of schizophrenia and schizoaffective disorder.

Indexed as

antipsychotic agentscognitive dysfunctiondopaminefamily characteristicspaliperidone palmitatepsychotic disordersserotonin

Identifiers

PMID34449689
PMCPMC8396046

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.