Evidence map›Paper›PMID 34449632›Full record

ArticleJournal of functional biomaterials2021

Formulation and Characterization of a New Injectable Bone Substitute Composed PVA/Borax/CaCO

Daniela Medrano-David, Aura María Lopera, Martha Elena Londoño, Pedronel Araque-Marín

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Obesity and lipid metabolism in the development of osteoporosis (Review).International journal of molecular medicine · 2024
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniela Medrano-DavidResearch Group GIBEC, Life Sciences Faculty, EIA University, Envigado 055420, Colombia.ORCID 0000-0002-5141-601X
Aura María LoperaResearch Group GIBEC, Life Sciences Faculty, EIA University, Envigado 055420, Colombia.
Martha Elena LondoñoResearch Group GIBEC, Life Sciences Faculty, EIA University, Envigado 055420, Colombia.ORCID 0000-0003-0576-4854
Pedronel Araque-MarínResearch and Innovation Group in Chemical Formulations, Life Sciences Faculty, EIA University, Envigado 055420, Colombia.

Funding

Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS) 133377757790
6 · The paper itself

Abstract

The occurrence of bone-related disorders and diseases has dramatically increased in recent years around the world. Demineralized bone matrix (DBM) has been widely used as a bone implant due to its osteoinduction and bioactivity. However, the use of DBM is limited because it is a particulate material, which makes it difficult to manipulate and implant with precision. In addition, these particles are susceptible to migration to other sites. To address this situation, DBM is commonly incorporated into a variety of carriers. An injectable scaffold has advantages over bone grafts or preformed scaffolds, such as the ability to flow and fill a bone defect. The aim of this research was to develop a DBM carrier with such viscoelastic properties in order to obtain an injectable bone substitute (IBS). The developed DBM carrier consisted of a PVA/glycerol network cross-linked with borax and reinforced with CaCO

Indexed as

bone graftbone tissue engineeringbone tissue regenerationfractureinjectableosteoblast

Identifiers

PMID34449632
PMCPMC8395841

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.