Evidence map›Paper›PMID 34449584›Full record

ReviewDermatopathology (Basel, Switzerland)2021

Aberrant Expression of Immunohistochemical Markers in Malignant Melanoma: A Review.

Elie Saliba, Jag Bhawan

Abstract readReview
In one paragraph

Review in Dermatopathology (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Melanoma in the Breast: A Diagnostic Challenge.The Yale journal of biology and medicine · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Amelanotic Melanoma: A Great Masquerader.Journal of laboratory physicians · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elie SalibaDermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118-2415, USA.
Jag BhawanDermatopathology Section, Department of Dermatology, Boston University School of Medicine, Boston, MA 02118-2415, USA.ORCID 0000-0001-9264-7300

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunohistochemical stains are increasingly used to aid in the diagnosis of malignant melanoma, especially when the differentiation of the tumor is unclear based on examination with hematoxylin and eosin. However, aberrant expression of non-melanocytic markers has been reported in melanomas, which can sometimes be further complicated by the loss of conventional melanocytic markers. This review aims to summarize available data regarding unusual staining patterns in primary and metastatic malignant melanoma. It also raises awareness of the potential pitfalls and highlights the importance of appropriate use and interpretation of broad immunohistochemical markers in the context of clinical and histopathologic findings to facilitate the diagnosis of atypical cases of malignant melanoma.

Indexed as

aberrant expressionimmunohistochemistrymalignant melanomamelanocytic markers

Identifiers

PMID34449584
PMCPMC8395931

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.