Evidence map›Paper›PMID 34449579›Full record

Observational studyCurrent oncology (Toronto, Ont.)2021

Peripheral Blood Lymphocyte Percentage May Predict Chemotolerance and Survival in Patients with Advanced Pancreatic Cancer. Association between Adaptive Immunity and Nutritional State.

Roberto Aquilani, Silvia Brugnatelli, Roberto Maestri, Federica Boschi, Beatrice Filippi, Lorenzo Perrone, Annalisa Barbieri, Daniela Buonocore, Maurizia Dossena, Manuela Verri

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Roberto AquilaniDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.
Silvia BrugnatelliMedical Oncology Division, Fondazione IRCCS, Policlinico San Matteo, 27100 Pavia, Italy.ORCID 0000-0003-0790-8380
Roberto MaestriDepartment of Biomedical Engineering of the Montescano Institute, Istituti Clinici Scientifici Maugeri IRCCS, 27040 Montescano, Italy.ORCID 0000-0002-2873-0430
Federica BoschiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Beatrice FilippiMedical Oncology Division, Fondazione IRCCS, Policlinico San Matteo, 27100 Pavia, Italy.
Lorenzo PerroneMedical Oncology Division, Fondazione IRCCS, Policlinico San Matteo, 27100 Pavia, Italy.
Annalisa BarbieriDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Daniela BuonocoreDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.
Maurizia DossenaDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.
Manuela VerriDepartment of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, 27100 Pavia, Italy.
University of Pavia · ITPoliclinico San Matteo Fondazione · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic Carcinoma (PC) cells have the ability to induce patient immunosuppression and to escape immunosurveillance. Low circulating lymphocytes are associated with an advanced stage of PC and reduced survival. Blood lymphocytes expressed as a percentage of Total White Blood Cells (L% TWBC) could predict chemotolerance (n° of tolerated cycles), survival time and Body Weight (BW) more effectively than lymphocytes expressed as an absolute value (L

Indexed as

Nutritional StatusPancreatic NeoplasmsAdaptive ImmunityHumansLymphocytesPrognosisRetrospective Studiesadvanced pancreatic cancerchemotoleranceimpaired adaptive immune responsenutritional statussurvival

Identifiers

PMID34449579
PMCPMC8395458
OpenAlexW3195568476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.