Evidence map›Paper›PMID 34449543›Full record

ArticleCurrent issues in molecular biology2021

Assessment and Clinical Utility of a Non-Next-Generation Sequencing-Based Non-Invasive Prenatal Testing Technology.

Uzay Gormus, Alka Chaubey, Suresh Shenoy, Yong Wee Wong, Lee Yin Chan, Bao Ping Choo, Liza Oraha, Anna Gousseva, Fredrik Persson, Lawrence Prensky and 2 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Advances in laboratory medicine · 2025
    Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Uzay GormusPerkinElmer Genomics Sweden, 191 38 Sollentuna, Sweden.
Alka ChaubeyPerkinElmer Genomics, Pittsburgh, PA 15275, USA.ORCID 0000-0002-0914-9237
Suresh ShenoyPerkinElmer Genomics, Pittsburgh, PA 15275, USA.
Yong Wee WongDNA Laboratories Sdn. Bhd, PerkinElmer Genomics Malaysia, Bangi 43650, Selangor, Malaysia.
Lee Yin ChanDNA Laboratories Sdn. Bhd, PerkinElmer Genomics Malaysia, Bangi 43650, Selangor, Malaysia.
Bao Ping ChooDNA Laboratories Sdn. Bhd, PerkinElmer Genomics Malaysia, Bangi 43650, Selangor, Malaysia.
Liza OrahaPerkinElmer Genomics Sweden, 191 38 Sollentuna, Sweden.
Anna GoussevaVanadis Diagnostics, PerkinElmer Inc., 191 38 Sollentuna, Sweden.
Fredrik PerssonVanadis Diagnostics, PerkinElmer Inc., 191 38 Sollentuna, Sweden.
Lawrence PrenskyPerkinElmer Inc., Waltham, MA 02451, USA.ORCID 0000-0003-4427-9122
Ephrem ChinPerkinElmer Genomics, Pittsburgh, PA 15275, USA.
Madhuri HegdePerkinElmer Genomics, Pittsburgh, PA 15275, USA.
PerkinElmer (United States) · USMalaysia Genome Institute · MYBioNano Genomics (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AneuploidyAdultCell-Free Nucleic AcidsDown SyndromeFemaleHigh-Throughput Nucleotide SequencingHumansMiddle AgedNoninvasive Prenatal TestingPregnancyTrisomy 13 SyndromeTrisomy 18 SyndromeYoung AdultCell-Free Nucleic Acidsaneuploidycell-free DNAdigital quantificationNIPSNIPTnoninvasive prenatal screeningnoninvasive prenatal testingprenatal screeningrolling-circle replicationvalidation study

Identifiers

PMID34449543
PMCPMC8929113
OpenAlexW3194639048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.