Evidence map›Paper›PMID 34449541›Full record

ArticleAudiology research2021

Benign Paroxysmal Positional Vertigo (BPPV) in COVID-19.

Pasqualina Maria Picciotti, Giulio Cesare Passali, Bruno Sergi, Eugenio De Corso

Abstract read
In one paragraph

Article in Audiology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. The Review of Ophthalmic Symptoms in COVID-19.Clinical ophthalmology (Auckland, N.Z.) · 2024
    Review
  4. Article
  5. Could vertigo be a post-COVID-19 sequela or presenting symptom?The Egyptian journal of neurology, psychiatry and neurosurgery · 2023
    Article
  6. Neuro-otological Symptoms: An Atypical Aspect of COVID-19 Disease.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  7. Therapeutic Approaches to the Neurologic Manifestations of COVID-19.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pasqualina Maria PicciottiOtolaryngology Institute-Department of Head and Neck, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Giulio Cesare PassaliOtolaryngology Institute-Department of Head and Neck, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Bruno SergiOtolaryngology Institute-Department of Head and Neck, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.
Eugenio De CorsoOtolaryngology Institute-Department of Head and Neck, Fondazione Policlinico Universitario A Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-5761-7018

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this article is to describe BPPV in COVID-19 patients by discussing the possible mechanisms underlying the onset of this vertigo.

methodsWe studied eight patients (4 F, 4 M, aged between 44 and 69 years) with COVID-19 infections complaining of vertigo. Patients were evaluated at the end of infection with an accurate clinical history, and the investigation of spontaneous, positional and positioning nystagmus.

resultsThe vestibular findings showed benign paroxysmal positional vertigo (BPPV) in all the patients. Three patients had a mild phenotype of the COVID infection, whereas five subjects were hospitalized for the COVID infection and in three cases intensive care was required. Vestibular evaluation showed an involvement of posterior semicircular canals in five patients and horizontal in three. Three patients were treated with the Epley maneuver, two with Semont, one with Lempert and two with Gufoni maneuvers.

conclusionsWe hypothesize that BPPV in COVID-19 infections can be relate to drugs, prolonged bed rest and to direct damage by viral infection on the peripheral vestibular system and in particular on the otolitic membrane due to the cytopathic effect of the virus and to the inflammatory response. Studies on large series of patients are needed to confirm our preliminary observation and to better evaluate the pathophysiological mechanisms underlying BPPV in these patients.

Indexed as

BPPVCOVID-19vertigovestibular

Identifiers

PMID34449541
PMCPMC8395413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.