Evidence map›Paper›PMID 34449494›Full record

ArticleMedicine2021

Palliation of malignant dysphagia with a segmented self-expanding metal stent: A STROBE-compliant article.

Marie-Sophie Wiese, Thomas Dratsch, Patrick Sven Plum, Florian Lorenz, Isabel Rieck, Daniel Pinto Dos Santos, Hakan Alakus, Marc Bludau, Robert Kleinert, Tobias Goeser and 2 more

Open access · goldAbstract read
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 3 countries.

Marie-Sophie WieseUniversity of Cologne, Cologne, Germany.
Thomas DratschDepartment of Radiology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Patrick Sven PlumDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Florian LorenzDepartment of Gastroenterology and Hepatology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Isabel RieckDepartment of Gastroenterology and Hepatology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Daniel Pinto Dos SantosDepartment of Radiology, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Hakan AlakusDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Marc BludauDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Robert KleinertDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Tobias Goeser
Christiane Josephine BrunsDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.
Seung-Hun ChonDepartment of General, Visceral, Cancer and Transplantation Surgery, University of Cologne, Faculty of Medicine, and University Hospital Cologne, Cologne, Germany.ORCID 0000-0002-8923-6428
University of Cologne · DEWeatherford College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractSelf-expanding metal stents (SEMSs) in different geometric shapes are an established palliative treatment for malignant tumors of the esophagus. Mechanical properties and stent design have an impact on patient comfort, migration rate, and removability. SEMS with a segmented design (segSEMS) have recently become available on the market, promising new biomechanical properties for stent placement in benign and malignant esophageal diseases. In this study, we evaluated recurrent dysphagia, quality of life as well as technical success and complications for segmented SEMS-implantation in a retrospective study in palliative patients with dysphagia caused by malignant tumors of the esophagus.Between May 2017 and December 2018, patients presented to the interdisciplinary department of endoscopy of the University Hospital Cologne underwent segmented SEMS placement for malignant dysphagia. Patient follow-up was evaluated, and complications were monitored. Quality of life and functional improvement were monitored using the EORTC QLQ-C30 and QLQ-OE18.A total of 20 consecutive patients (16 men, 4 women; mean age: 65.5, range: 46-82) participated in the study and were treated with 20 segSEMS in total. The success rate of stent placement was 100%. Stent migration occurred in 3 patients (15.0%). Insertion of segSEMS immediately lead to a 48.0% reduction of dysphagia in the first 2 months (P < .001). Pain while eating (odynophagia) could also be significantly reduced by 39.6% over the first 2 months (P < .001).Implantation of segSEMS is a feasible and effective treatment for dysphagia in palliative patients with malignant tumors of the esophagus, offering immediate relief of symptoms and gain of physical functions.

Indexed as

AgedAged, 80 and overDeglutition DisordersEsophageal NeoplasmsFemaleHumansMaleMiddle AgedNeoplasm StagingPalliative CareQuality of LifeRetrospective StudiesSelf Expandable Metallic Stents

Identifiers

PMID34449494
PMCPMC10545253
OpenAlexW3195407211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.