Evidence map›Paper›PMID 34449285›Full record

Trial reportAmerican journal of respiratory and critical care medicine2022

Randomized Clinical Trial of Air Cleaners to Improve Indoor Air Quality and Chronic Obstructive Pulmonary Disease Health: Results of the CLEAN AIR Study.

Nadia N Hansel, Nirupama Putcha, Han Woo, Roger Peng, Gregory B Diette, Ashraf Fawzy, Robert A Wise, Karina Romero, Meghan F Davis, Ana M Rule and 4 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Health effects of air pollution on chronic respiratory diseases.The Korean journal of internal medicine · 2026
    Review
  8. Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026
    Review
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Nadia N HanselDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Nirupama PutchaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Han WooDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Roger PengDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and.
Gregory B DietteDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Ashraf FawzyDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Robert A WiseDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0002-8353-2349
Karina RomeroDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Meghan F DavisDepartment of Environmental Health and Engineering and.
Ana M RuleDepartment of Environmental Health and Engineering and.
Michelle N EakinDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Patrick N BreysseDepartment of Environmental Health and Engineering and.
Meredith C McCormackDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.ORCID 0000-0003-1702-3201
Kirsten KoehlerDepartment of Environmental Health and Engineering and.
Johns Hopkins University · USCenters for Disease Control and Prevention · US

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Clinical trial of air cleaners to improve indoor air quality and COPD healthR01ES022607 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2013 to 2017
$3.4M
NHLBI NIH HHS T32 HL007534NHLBI NIH HHS T32HL007534NIEHS NIH HHS R01 ES022607NIEHS NIH HHS R01ES022607
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Air FiltersAdultAgedAged, 80 and overAir Pollution, IndoorDisease ProgressionDouble-Blind MethodFemaleHumansIntention to Treat AnalysisMaleMiddle AgedPulmonary Disease, Chronic ObstructiveTreatment OutcomeWalk Testair filtersclinical trialCOPDenvironmentparticulate matter

Identifiers

PMID34449285
PMCPMC8886948
OpenAlexW3194555754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.