Evidence map›Paper›PMID 34449050›Full record

ArticleJournal of cancer survivorship : research and practice2022

Resignation and return to work in patients receiving allogeneic hematopoietic cell transplantation close up.

Saiko Kurosawa, Takuhiro Yamaguchi, Ayako Mori, Tomoko Matsuura, Takehiko Mori, Masatsugu Tanaka, Tadakazu Kondo, Yukari Umemoto, Hideki Goto, Satoshi Yoshioka and 10 more

Erratum issuedAbstract read
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In one paragraph

Article in Journal of cancer survivorship : research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Factors associated with employment outcomes in cancer survivors: a systematic scoping review spanning a decade of international research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 17 institutions in 1 country.

Saiko KurosawaDepartment of Oncology, Ina Central Hospital, 1313-1 Koshiro-kubo, Ina, Nagano, 396-8555, Japan. skurosaw@inahp.jp.ORCID 0000-0002-6819-9381
Takuhiro YamaguchiDivision of Biostatistics, Tohoku University Graduate School of Medicine, Sendai, Japan.
Ayako MoriNursing Division, National Cancer Center Hospital, Tokyo, Japan.
Tomoko MatsuuraNursing Division, National Cancer Center Hospital, Tokyo, Japan.
Takehiko MoriDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Masatsugu TanakaDepartment of Hematology, Kanagawa Cancer Center, Yokohama, Japan.
Tadakazu KondoDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yukari UmemotoDepartment of Hematology, Osaka City University Hospital, Osaka, Japan.
Hideki GotoDepartment of Hematology, Hokkaido University Hospital, Sapporo, Japan.
Satoshi YoshiokaDepartment of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan.
Shinichiro MachidaDepartment of Hematology and Oncology, Tokai University School of Medicine, Isehara, Japan.
Takahiko SatoDepartment of Hematology, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan.
Yuta KatayamaDepartment of Hematology, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan.
Seiko KatoDepartment of Hematology/Oncology Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Katsuhiro ShonoDepartment of Hematology, Chiba Aoba Municipal Hospital, Chiba, Japan.
Ishikazu MizunoDepartment of Hematology, Hyogo Cancer Center, Hyogo, Japan.
Shin-Ichiro FujiwaraDivision of Hematology, Jichi Medical University Hospital, Shimotsuke, Japan.
Akio KohnoDepartment of Hematology and Oncology, Konan Kosei Hospital, Konan, Japan.
Miyako TakahashiDivision of Cancer Survivorship Research, National Cancer Center, Tokyo, Japan.
Takahiro FukudaDepartment of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
Chiba Aoba Municipal Hospital · JPHiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital · JPHokkaido University Hospital · JPHyogo Prefectural Cancer Center · JPJichi Medical University · JPKanagawa Prefectural Hospital Organization · JPKeio University · JPKobe City Medical Center General Hospital · JPKonan Kosei Hospital · JPKubota (Japan) · JPKyoto University · JPNational Hospital Organization Kyushu Cancer Center · JPOsaka City University Hospital · JPThe University of Tokyo · JPTohoku University · JPTokai University · JPTokyo National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo characterize the issues regarding work and employment specific to allogeneic hematopoietic cell transplantation (allo-HCT) survivors, we conducted a nationwide cross-sectional questionnaire survey.

methodsWe targeted allo-HCT survivors employed at diagnosis, aged 20-64 at survey, and survived ≥2 years without relapse. The questionnaire included the timing of and reasons for resignation (termination of employment contract), and patient-related, HCT-related, work-related, and HCT center-related factors.

resultsA total of 1048 eligible participants were included in the analysis (response rate, 60%). The median time after allo-HCT was 5 years (range, 2-30) at the time of survey. After diagnosis, 41% of participants resigned from work throughout the course of treatment. The most frequent timing of the first resignation was "after discharge post-HCT" (46%), followed by "from diagnosis to initial treatment" (27%). Factors significantly associated with resignation included female gender, older age, and part-time employment. Favorable factors included the presence of occupational health staff at the workplace, employment of ≥10 years, and self-employed/freelance. After resignation, the overall incidence of return to work with some accommodations was 76% at 5 years after HCT, but it was 52% without any accommodation.

conclusionsOverall, the rate of resignation was 41%, and the most frequent timing of resignation was after discharge post-HCT, accounting for approximately half of the resignations (46%). Workplace accommodations increased the rate of return to work from 52% to 76%. IMPLICATIONS FOR CANCER SURVIVORS: Early detection of employment-related concerns and support throughout the treatment process are necessary for patients receiving allo-HCT.

Indexed as

Hematopoietic Stem Cell TransplantationReturn to WorkCross-Sectional StudiesEmploymentFemaleHumansSurvivorsAllogeneic hematopoietic cell transplantationResignation from work, employment, return to workSurvivorship

Identifiers

PMID34449050
OpenAlexW3194443542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.