Evidence map›Paper›PMID 34448691›Full record

ArticleMicrobial genomics2021

Adaptive response to wine selective pressures shapes the genome of a

María Lairón-Peris, Gabriel L Castiglioni, Sarah J Routledge, Javier Alonso-Del-Real, John A Linney, Andrew R Pitt, Josef Melcr, Alan D Goddard, Eladio Barrio, Amparo Querol

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Theoretical Study of Sphingomyelinases fromPathogens (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

María Lairón-PerisDepartamento de Biotecnología de los Alimentos, Instituto de Agroquímica y Tecnología de los Alimentos, CSIC, Valencia, Spain.
Gabriel L CastiglioniDepartamento de Biotecnología de los Alimentos, Instituto de Agroquímica y Tecnología de los Alimentos, CSIC, Valencia, Spain.
Sarah J RoutledgeCollege of Health and Life Sciences, Aston University, Birmingham, UK.
Javier Alonso-Del-RealDepartamento de Biotecnología de los Alimentos, Instituto de Agroquímica y Tecnología de los Alimentos, CSIC, Valencia, Spain.
John A LinneyCollege of Health and Life Sciences, Aston University, Birmingham, UK.
Andrew R PittCollege of Health and Life Sciences, Aston University, Birmingham, UK.
Josef MelcrGroningen Biomolecular Sciences and Biotechnology Institute and the Zernike Institute for Advanced Material, University of Groningen, Groningen, The Netherlands.
Alan D GoddardCollege of Health and Life Sciences, Aston University, Birmingham, UK.
Eladio BarrioDepartamento de Biotecnología de los Alimentos, Instituto de Agroquímica y Tecnología de los Alimentos, CSIC, Valencia, Spain.
Amparo QuerolDepartamento de Biotecnología de los Alimentos, Instituto de Agroquímica y Tecnología de los Alimentos, CSIC, Valencia, Spain.
Aston University · GBInstituto de Agroquímica y Tecnología de Alimentos · ESUniversitat de València · ESUniversity of Groningen · NL

Funding

Biotechnology and Biological Sciences Research Council BB/R02152X/1
6 · The paper itself

Abstract

During industrial processes, yeasts are exposed to harsh conditions, which eventually lead to adaptation of the strains. In the laboratory, it is possible to use experimental evolution to link the evolutionary biology response to these adaptation pressures for the industrial improvement of a specific yeast strain. In this work, we aimed to study the adaptation of a wine industrial yeast in stress conditions of the high ethanol concentrations present in stopped fermentations and secondary fermentations in the processes of champagne production. We used a commercial

Indexed as

Genome, FungalAdaptation, PhysiologicalEthanolFermentationSaccharomycesSaccharomyces cerevisiaeTranscriptomeWineEthanoladaptationartificial hybridgenome sequencingRNA-seqSaccharomyces cerevisiaeS. uvarum

Identifiers

PMID34448691
PMCPMC8549368
OpenAlexW3194488329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.