Evidence map›Paper›PMID 34448640›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

Adverse childhood events and cardiovascular diseases: the potential role of Sirt1.

Paula Rodriguez-Miguelez, Jennifer S Pollock

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Practitioner Review: Infant mental health meets cell and molecular biology - a look to the future.Journal of child psychology and psychiatry, and allied disciplines · 2026
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Paula Rodriguez-MiguelezDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond, Virginia.ORCID 0000-0003-3582-4483
Jennifer S PollockCardio-Renal Physiology and Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-1956-0449

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
Clinical and Translational Science Awards Program, National Institute of Health to VCU UL1TR002649NCATS NIH HHS UL1 TR002649NIDDK NIH HHS P30 DK079626Program Project Grant from National Institutes of Health P01HL136237
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesSirtuin 1ChildHumansNitric Oxide Synthase Type IIIVasodilationNitric Oxide Synthase Type IIISIRT1 protein, humanSirtuin 1adverse childhood eventsearly life stressnitric oxideSirt1vascular function

Identifiers

PMID34448640
PMCPMC8461843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.