Evidence map›Paper›PMID 34448486›Full record

ArticleFamily practice2021

COVID-19 and the flu: data simulations and computational modelling to guide public health strategies.

Verda Tunaligil, Gulsen Meral, Mustafa Resat Dabak, Mehmet Canbulat, Sıddıka Semahat Demir

Erratum issuedAbstract read
In one paragraph

Article in Family practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Verda TunaligilSIMMERK Medical Simulation Center, Division of Public Health and Department of Emergency, Disaster Medical Services, TR MoH Health Directorate of Istanbul, Istanbul, Turkey.ORCID 0000-0002-4965-9231
Gulsen MeralPresident's Office and Department of Pediatrics, Nutrigenetics and Epigenetics Association, Istanbul, Turkey.ORCID 0000-0002-0567-7702
Mustafa Resat DabakDepartment of Family Medicine, Divisions of Residency Training Programs and Clinical Practice Chieftaincy, TR MoH Haseki Research and Training Hospital, Istanbul, Turkey.ORCID 0000-0002-0200-5409
Mehmet CanbulatDepartment of Data Management, Turkish Airlines, Istanbul, Turkey.ORCID 0000-0002-3332-7304
Sıddıka Semahat DemirPresident's Office and Departments of Biomedical, Electrical, Computer Engineering, Science Heroes Association, Istanbul, Turkey.ORCID 0000-0003-2086-9953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPandemics threaten lives and economies. This article addresses the global threat of the anticipated overlap of COVID-19 with seasonal-influenza.

objectivesScientific evidence based on simulation methodology is presented to reveal the impact of a dual outbreak, with scenarios intended for propagation analysis. This article aims at researchers, clinicians of family medicine, general practice and policy-makers worldwide. The implications for the clinical practice of primary health care are discussed. Current research is an effort to explore new directions in epidemiology and health services delivery.

methodsProjections consisted of machine learning, dynamic modelling algorithms and whole simulations. Input data consisted of global indicators of infectious diseases. Four simulations were run for '20% versus 60% flu-vaccinated populations' and '10 versus 20 personal contacts'. Outputs consisted of numerical values and mathematical graphs. Outputs consisted of numbers for 'never infected', 'vaccinated', 'infected/recovered', 'symptomatic/asymptomatic' and 'deceased' individuals. Peaks, percentages, R0, durations are reported.

resultsThe best-case scenario was one with a higher flu-vaccination rate and fewer contacts. The reverse generated the worst outcomes, likely to disrupt the provision of vital community services. Both measures were proven effective; however, results demonstrated that 'increasing flu-vaccination rates' is a more powerful strategy than 'limiting social contacts'.

conclusionsResults support two affordable preventive measures: (i) to globally increase influenza-vaccination rates, (ii) to limit the number of personal contacts during outbreaks. The authors endorse changing practices and research incentives towards multidisciplinary collaborations. The urgency of the situation is a call for international health policy to promote interdisciplinary modern technologies in public health engineering.

Indexed as

Global HealthPublic Health PracticeCommunicable Disease ControlComputer SimulationCOVID-19COVID-19 VaccinesDisease OutbreaksHumansInfluenza, HumanInfluenza VaccinesPandemicsPlanning TechniquesPneumonia, ViralSARS-CoV-2COVID-19 VaccinesInfluenza VaccinesArtificial learningcoronavirusinfluenzaSARS-CoV-2social distancingvaccination

Identifiers

PMID34448486
PMCPMC8499780

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.