Evidence map›Paper›PMID 34448080›Full record

SynthesisNeurosurgical review2022

External ventricular drain management in subarachnoid haemorrhage: a systematic review and meta-analysis.

Joanna Palasz, Linda D'Antona, Sarah Farrell, Mohamed A Elborady, Laurence D Watkins, Ahmed K Toma

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joanna PalaszVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK. jopalasz@gmail.com.ORCID http://orcid.org/0000-0003-0559-3725
Linda D'AntonaVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK.
Sarah FarrellVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK.
Mohamed A ElboradyVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK.
Laurence D WatkinsVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK.
Ahmed K TomaVictor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, Box 32, London, WC1N 3BG, UK.
National Hospital for Neurology and Neurosurgery · GBThe Royal Free Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

External ventricular drainage (EVD) is one of the most commonly performed neurosurgical procedures. Despite this, the optimal drainage and weaning strategies are still unknown. This PRISMA-compliant systematic review and meta-analysis analysed the outcomes of patients undergoing EVD procedures, comparing continuous versus intermittent drainage and rapid versus gradual weaning. Four databases were searched from inception to 01/10/2020. Articles reporting at least 10 patients treated for hydrocephalus secondary to subarachnoid haemorrhage were included. Other inclusion criteria were the description of the EVD drainage and weaning strategies used and a comparison of continuous versus intermittent drainage or rapid versus gradual weaning within the study. Random effect meta-analyses were used to compare functional outcomes, incidence of complications and hospital length of stay. Intermittent external CSF drainage was associated with lower incidence of EVD-related infections (RR = 0.20, 95% CI 0.05-0.72, I-squared = 0%) and EVD blockages compared to continuous CSF drainage (RR = 0.45, 95% CI 0.27-0.74, I-squared = 0%). There was no clear advantage in using gradual EVD weaning strategies compared to rapid EVD weaning; however, patients who underwent rapid EVD weaning had a shorter hospital length of stay (SMD = 0.34, 95% CI 0.22-0.47, I-squared = 0%). Intermittent external CSF drainage after SAH is associated with lower incidence of EVD-related infections and EVD blockages compared to continuous CSF drainage. Patients who underwent rapid EVD weaning had a shorter hospital length of stay and there was no clear clinical advantage in using gradual weaning.

Indexed as

HydrocephalusSubarachnoid HemorrhageDrainageHumansNeurosurgical ProceduresVentriculostomyCerebrospinal fluid drainageExternal ventricular drainHydrocephalusSubarachnoid haemorrhageVentriculostomy

Identifiers

PMID34448080
OpenAlexW3194424632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.