ArticleEuropean radiology2022
Diagnostic and prognostic values of 2-[
Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Prognostic Significance of Pretreatment ¹⁸F-FDG PET/CT Parameters in Patients With ER+/HER2- Metastatic Breast Cancer Treated With CDK4/6 Inhibitors Plus Endocrine Therapy.Korean journal of radiology · 2026Article
- Prognostic value as metabolic tumor activity onJournal of thoracic disease · 2026Article
- Prognostic and predictive biomarkers in thymic epithelial tumors: beyond traditional staging: a narrative review.Mediastinum (Hong Kong, China) · 2026Review
- Serial positron-emission tomography after induction therapy as a predictor of prognostic outcomes for patients with thymic carcinoma.Surgery today · 2025Article
- Clinical significance of positron emission tomography-computed tomography in the classification of thymic tumors.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- The Role of [Molecular diagnosis & therapy · 2025Article
- Identifying small thymomas from other asymptomatic anterior mediastinal nodules based on CT images using logistic regression.Frontiers in oncology · 2025Article
- Distinguishing thymic cysts from low-risk thymomas via [EJNMMI research · 2024Article
- A diagnostic model based onBMC medical imaging · 2024Article
- Impact ofAnnals of surgical oncology · 2024Article
- [Scientific reports · 2023Article
- Superiority of [European journal of nuclear medicine and molecular imaging · 2023Article
- Is PET/CT Able to Predict Histology in Thymic Epithelial Tumours? A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
- Multiparameter diagnostic model based onBMC cancer · 2022Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
objectivesWe aimed to evaluate the diagnostic ability for the prediction of histologic grades and prognostic values on recurrence and death of pretreatment 2-[
methodsOne hundred and fourteen patients with TETs who underwent pretreatment 2-[
resultsThe tumours included 52 LRT, 33 HRT, and 29 TC. SUVmax showed good diagnostic ability for differentiating HRT/TC from LRT (AUC 0.84, 95% confidence interval [CI] 0.76 - 0.92) and excellent ability for differentiating TC from LRT/HRT (AUC 0.94, 95% CI 0.90 - 0.98), with significantly higher values than MTV, TLG, and maximum diameter. With an optimal cut-off value of 6.4, the sensitivity, specificity, and accuracy for differentiating TC from LRT/HRT were 69%, 96%, and 89%, respectively. In the multivariable Cox proportional hazards analyses for freedom-from-recurrence, SUVmax was an independent prognostic factor (p < 0.001), whereas MTV and TLG were not. SUVmax was a significant predictor for overall survival in conjunction with clinical stage and resection margin.
conclusionSUVmax showed excellent diagnostic performance for prediction of TC and significant prognostic value in terms of recurrence and survival. KEY POINTS: • Maximum standardised uptake value (SUVmax) shows excellent performance in the differentiation of thymic carcinoma from low- and high-risk thymoma. • SUVmax is an independent prognostic factor for freedom-from-recurrence in the multivariable Cox proportional hazard model and a significant predictor for overall survival. • 2-[
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