Evidence map›Paper›PMID 34447843›Full record

ArticleWorld journal of clinical cases2021

Complete withdrawal of glucocorticoids after dupilumab therapy in allergic bronchopulmonary aspergillosis: A case report.

Tadashi Nishimura, Tomohito Okano, Masahiro Naito, Chikashi Tsuji, Soichi Iwanaka, Yasumasa Sakakura, Taro Yasuma, Hajime Fujimoto, Corina N D'Alessandro-Gabazza, Yasuhiro Oomoto and 3 more

Abstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Biologic drugs in treating allergic bronchopulmonary aspergillosis in patients with cystic fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2022
    Pooled it
  3. Treatment of allergic bronchopulmonary aspergillosis with biologics.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Severe Fungal Asthma: A Role for Biologics and Inhaled Antifungals.Journal of fungi (Basel, Switzerland) · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tadashi NishimuraDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Tomohito OkanoDepartment of Pulmonary and Critical Care Medicine, Mie University, Tsu 514-8507, Mie, Japan.
Masahiro NaitoDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Chikashi TsujiDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Soichi IwanakaDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Yasumasa SakakuraDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Taro YasumaDepartment of Immunology, Mie University School of Medicine, Mie University, Tsu 514-8507, Mie, Japan.
Hajime FujimotoDepartment of Pulmonary and Critical Care Medicine, Mie University, Tsu 514-8507, Mie, Japan.
Corina N D'Alessandro-GabazzaDepartment of Immunology, Mie University School of Medicine, Mie University, Tsu 514-8507, Mie, Japan.
Yasuhiro OomotoDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.
Tetsu KobayashiDepartment of Pulmonary and Critical Care Medicine, Graduate School of Medicine Mie, Mie University, Tsu 514-8507, Mie, Japan.
Esteban C GabazzaDepartment of Immunology, Mie University School of Medicine, Mie University, Tsu 514-8507, Mie, Japan. gabazza@doc.medic.mie-u.ac.jp.
Hidenori IbataDepartment of Pulmonary Medicine, Mie Chuo Medical Center, Tsu 514-1101, Mie, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction to CASE SUMMARY: The patient was a 54-year-old woman with bronchial asthma treated with inhaled corticosteroids and a long-acting beta-2 agonist. She consulted our institution for productive cough and fever in March 2017. Chest computed tomography scan revealed mucoid impaction, and the bronchial lavage fluid culture was positive for

conclusionThis is the first case of ABPA in which complete withdrawal of glucocorticoid was possible after treatment with dupilumab.

Indexed as

Allergic bronchopulmonary aspergillosisAsthmaCase reportDupilumabInterleukin-13Interleukin-4

Identifiers

PMID34447843
PMCPMC8362523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.