Evidence map›Paper›PMID 34447812›Full record

ReviewWorld journal of clinical cases2021

Intestinal microbiota participates in nonalcoholic fatty liver disease progression by affecting intestinal homeostasis.

Yang Zhang, Jun-Xiang Li, Yan Zhang, Yun-Liang Wang

Abstract readReview
In one paragraph

Review in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang ZhangDepartment of Gastroenterology, Dong Fang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
Jun-Xiang LiDepartment of Gastroenterology, Dong Fang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
Yan ZhangDepartment of Gastroenterology, Dong Fang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China.
Yun-Liang WangDepartment of Gastroenterology, Dong Fang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China. yunliang_wang@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease with a pathogenesis that has not been fully elucidated. With the development of the theory of the gut-liver axis and the deepening of related research, the role of the intestinal tract in the pathogenesis of NAFLD has been investigated more. Intestinal microbiota, intestinal metabolites, and intestinal epithelial and immune-based barriers constitute the intestinal environment, which uses crosstalk to maintain the homeostasis of the intestinal environment. This paper reviews the progress in the study of intestinal microbiota, intestinal environment, and NAFLD and suggests that repair of intestinal functional balance may be a new idea for early prevention and intervention of NAFLD.

Indexed as

Gut-liver axisIntestinal homeostasisIntestinal microbiotaMetabolitesNonalcoholic fatty liver disease

Identifiers

PMID34447812
PMCPMC8362529

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.