Evidence map›Paper›PMID 34447778›Full record

ReviewFrontiers in nutrition2021

Transcriptomic Effects of Healthspan-Promoting Dietary Interventions: Current Evidence and Future Directions.

Devin Wahl, Thomas J LaRocca

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Increasing the health span: unique role for exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Editorial: Nutrition and metabolic aging.Frontiers in nutrition · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Devin WahlDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States.
Thomas J LaRoccaDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States.

Funding

Inclusive Transcriptomics to Uncover Molecular Mechanisms Underlying HealthspanR21AG060302 · NIA · COLORADO STATE UNIVERSITY · PI LAROCCA, THOMAS · 2019 to 2020
$765k
Role of repetitive element transcripts in brain aging and Alzheimer's diseaseF32AG069361 · NIA · COLORADO STATE UNIVERSITY · PI WAHL, DEVIN · 2021 to 2023
$210k
NIA NIH HHS F32 AG069361NIA NIH HHS R21 AG060302
6 · The paper itself

Abstract

Aging is the greatest risk factor most diseases, including cardiovascular disorders, cancers, diabetes, and neurodegeneration, but select nutritional interventions may profoundly reduce the risk for these conditions. These interventions include calorie restriction, intermittent fasting, protein restriction, and reducing intake of certain amino acids. Certain

Indexed as

aginghealthspannutritionRNA-Seq - RNA sequencingtranscriptome

Identifiers

PMID34447778
PMCPMC8383293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.