ArticleFrontiers in nutrition2021
Type 2 Diabetes Mellitus: A Pathophysiologic Perspective.
Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Quantitative susceptibility mapping for iron monitoring of multiple subcortical nuclei in type 2 diabetes mellitus: a systematic review and meta-analysis.Frontiers in endocrinology · 2024Pooled it
- Biochemical and Molecular Markers Among Prediabetic and Type 2 Diabetes Mellitus Patients.International journal of endocrinology and metabolism · 2026Article
- Associations of Mediterranean, DASH, and MIND diet adherence with metabolic parameters in individuals with type 2 diabetes mellitus: a cross-sectional study.Irish journal of medical science · 2026Article
- Exploring Treatment Paradigms in Type 2 Diabetes: A Comparison of Independent and Combined Therapeutic Approaches.Cureus · 2026Review
- Combined In Vitro and Computational Investigations on Synthesized Sulfonamide-Based Antidiabetic Agents.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Integrating Phytochemical Bioactivity and Glycemic Risk to Evaluate Fruits for Type 2 Diabetes Management: A Korean Market Perspective.Foods (Basel, Switzerland) · 2026Article
- Network and molecular insights into the antidiabetic potential of squalene in alloxan-induced diabetes.Scientific reports · 2026Article
- Article
- Therapeutic potential of natural compounds from medicinal and food homology substances targeting gut microbiota in lipid metabolism disorders.Frontiers in microbiology · 2026Review
- scFv-based biologics in diabetes: from therapeutic potential to clinical prospects.Frontiers in immunology · 2026Review
- Effects of a health literacy program on self-management behaviors of patients with uncontrolled type 2 diabetes in Thailand: A quasi-experimental study.Belitung nursing journal · 2026Article
- Molecular mechanisms linking adipose tissue-derived small extracellular vesicles/exosomes to the development or amelioration of obesity, insulin resistance, and diabetes-related complications.European journal of medical research · 2025Review
- Inconvenience, lifestyle flexibility, glycemic control, and satisfaction with insulin treatment among patients with diabetes mellitus in palestine: a cross-sectional study.Scientific reports · 2025Article
- Prevalence of macro-vascular complications among type 2 diabetic adults aged 50 and over: results from Ardakan cohort study on aging (ACSA).Journal of diabetes and metabolic disorders · 2025Article
- Circulating CCN6/WISP3 in type 2 diabetes mellitus patients and its correlation with insulin resistance and inflammation: statistical and machine learning analyses.BMC medical informatics and decision making · 2025Article
- Assessment of Diabetes-Related Knowledge and Dietary Patterns Among Type 2 Diabetes Mellitus Patients in Central Saudi Arabia: Insights for Tailored Health Education Strategies.Healthcare (Basel, Switzerland) · 2025Article
- A Comprehensive Review on the Application of Marketed Drugs as Ligands through Metallopharmaceutics.Current topics in medicinal chemistry · 2025Review
- Article
- Nutrient metabolism and complications of type 2 diabetes mellitus: implications for rehabilitation and precision care.Frontiers in nutrition · 2025Review
- Risk factors for diabetic retinopathy in young and middle-aged patients: a retrospective study.BMC ophthalmology · 2024Article
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Authors and funding
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Abstract
Type 2 Diabetes Mellitus (T2DM) is characterized by chronically elevated blood glucose (hyperglycemia) and elevated blood insulin (hyperinsulinemia). When the blood glucose concentration is 100 milligrams/deciliter the bloodstream of an average adult contains about 5-10 grams of glucose. Carbohydrate-restricted diets have been used effectively to treat obesity and T2DM for over 100 years, and their effectiveness may simply be due to lowering the dietary contribution to glucose and insulin levels, which then leads to improvements in hyperglycemia and hyperinsulinemia. Treatments for T2DM that lead to improvements in glycemic control and reductions in blood insulin levels are sensible based on this pathophysiologic perspective. In this article, a pathophysiological argument for using carbohydrate restriction to treat T2DM will be made.
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