Evidence map›Paper›PMID 34447687›Full record

ReviewJournal of clinical and translational hepatology2021

Special Considerations in the Management of Autoimmune Hepatitis in COVID-19 Hotspots: A Review.

Deepak Madhu, Sanchit Sharma, Ashish Agarwal, Anoop Saraya

Abstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. COVID-19 Infection, Drugs, and Liver Injury.Journal of clinical medicine · 2025
    Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deepak MadhuDepartment of Gastroenterology, Aster MIMS Calicut, Kerala, India.ORCID https://orcid.org/0000-0002-8613-8670
Sanchit SharmaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0001-8551-5908
Ashish AgarwalDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0002-9729-891X
Anoop SarayaDepartment of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0002-3921-6752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing coronavirus disease-2019 (COVID-19) pandemic has necessitated special considerations in the management of diseases. The way presence of pre-existing diseases or treatment for it predisposes to, alters course of, and changes the management of COVID-19, is of relevance and is being extensively studied. Autoimmune hepatitis (AIH) is unique in that it is an autoimmune disease mandating treatment with immunosuppressive drugs, as well as a liver disease with potential for varying degrees of underlying fibrosis. The use of immunosuppressive drugs could alter the risk of acquiring COVID-19, the clinical course and severity of COVID-19 and the degree of underlying liver fibrosis could alter the clinical outcomes of patients with COVID-19. In this review, we try to summarize key areas relevant in understanding and improving the clinical care of patients with AIH in the current pandemic. Special considerations required in the management of patients with AIH in COVID-19 hotspots have been outlined based on the current evidence.

Indexed as

AutoimmuneCOVID-19HepatitisImmunosuppressive agentsLiver cirrhosisSARS-CoV-2 infection

Identifiers

PMID34447687
PMCPMC8369025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.