Evidence map›Paper›PMID 34447677›Full record

ArticleJournal of clinical and translational hepatology2021

Serum Resistin Levels in Adult Patients with Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis.

Dongli Han, Jie Chen, Shousheng Liu, Zengzhi Zhang, Zhenzhen Zhao, Wenwen Jin, Yongning Xin

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical and translational hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Dongli HanDepartment of Infectious Disease, Qingdao Municipal Hospital, Dalian Medical University, Dalian, Liaoning, China.
Jie ChenQingdao City Shinan District Centers for Disease Control and Prevention, Qingdao, Shandong, China.
Shousheng LiuClinical Research Center, Qingdao Municipal Hospital, Qingdao, Shandong, China.
Zengzhi ZhangQingdao City Shinan District Centers for Disease Control and Prevention, Qingdao, Shandong, China.
Zhenzhen ZhaoClinical Research Center, Qingdao Municipal Hospital, Qingdao, Shandong, China.
Wenwen JinDepartment of Infectious Disease, Qingdao Municipal Hospital, Dalian Medical University, Dalian, Liaoning, China.
Yongning XinDepartment of Infectious Disease, Qingdao Municipal Hospital, Dalian Medical University, Dalian, Liaoning, China.
Qingdao Municipal Hospital · CNQingdao Municipal Center for Disease Control and Prevention · CNDalian Medical University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPrevious studies reported that serum resistin levels were remarkably changed in patients with nonalcoholic fatty liver disease (NAFLD) but the conclusions were inconsistent. The aim of this study was to investigate accurate serum resistin levels in adult patients with NAFLD.

methodsA complete literature research was conducted in the PubMed, Embase, and Cochrane Library databases, and all the available studies up to 7 May 2020 were reviewed. The pooled standardized mean difference (SMD) values were calculated to investigate the serum resistin levels in patients with NAFLD and healthy controls.

resultsA total of 28 studies were included to investigate the serum resistin levels in patients with NAFLD. Patients with NAFLD had higher serum resistin levels than controls (SMD=0.522, 95% confidence interval [CI]: 0.004-1.040,

conclusionsThis meta-analysis investigated the serum resistin levels in adult patients with NAFLD comprehensively. Patients with NAFLD had higher serum resistin levels and patients with NASH had lower serum resistin levels than healthy controls. Serum resistin could serve as a potential biomarker to predict the development risk of NAFLD.

Indexed as

BiomarkerNonalcoholic fatty liver diseaseNonalcoholic steatohepatitisResistin

Identifiers

PMID34447677
PMCPMC8369026
OpenAlexW3161182072

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.