Evidence map›Paper›PMID 34447476›Full record

ReviewExperimental and therapeutic medicine2021

Gastro-intestinal dysfunctions in Parkinson's disease (Review).

Irina-Florina Ivan, Valentina-Laura Irincu, Ștefania Diaconu, Oana Falup-Pecurariu, Bogdan Ciopleiaș, Cristian Falup-Pecurariu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
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  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Irina-Florina IvanDepartment of Neurology, County Emergency Clinic Hospital, 500365 Brașov, Romania.
Valentina-Laura IrincuDepartment of Neurology, County Emergency Clinic Hospital, 500365 Brașov, Romania.
Ștefania DiaconuFaculty of Medicine, Transilvania University, 500036 Brașov, Romania.
Oana Falup-PecurariuFaculty of Medicine, Transilvania University, 500036 Brașov, Romania.
Bogdan CiopleiașDepartment of Neurology, County Emergency Clinic Hospital, 500365 Brașov, Romania.
Cristian Falup-PecurariuDepartment of Neurology, County Emergency Clinic Hospital, 500365 Brașov, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In patients with Parkinson's disease (PD), gastrointestinal dysfunction occurs from the early stages of the disease and even in the pre-motor phase. This condition can include the entire digestive tract, with symptoms ranging from delays in gastric emptying to dysphagia, constipation and even malnutrition. Excess saliva accumulates in the mouth due to the low frequency of swallowing. Dysphagia develops in about 50% of patients and may be a reflection of both central nervous system and enteric nervous system disorder. Gastroparesis can cause a variety of symptoms, including nausea, and also may be responsible for some of the motor fluctuations observed with levodopa therapy. Intestinal dysfunction in PD may be the result of both delayed colon transit and impaired anorectal muscle coordination. In addition, recent studies have demonstrated the role of

Indexed as

constipationdroolingdysphagiagastrointestinal dysfunctiongastroparesisParkinson's disease

Identifiers

PMID34447476
PMCPMC8355716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.