Evidence map›Paper›PMID 34447473›Full record

ArticleExperimental and therapeutic medicine2021

Thickening of the walls of deep brain abscesses is associated with macrophage infiltration.

Zuocheng Yang, Yakun Yang, Xueling Qi, Ning Liu, Pengfei Wang, Linpeng Zhang, Mingyang Han, Song Han

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zuocheng YangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Yakun YangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Xueling QiDepartment of Pathology, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Ning LiuDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Pengfei WangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Linpeng ZhangDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Mingyang HanDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Song HanDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100093, P.R. China.
Capital Medical University · CNBeijing Sanbo Brain Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to compare the thickness of brain abscesses in the deep and the superficial brain and to investigate the factors that influence the capsule of brain abscesses. The thickness of the brain abscess wall was evaluated on imaging. Bacteriological examination was performed on the abscess pus and wall, and immunohistochemical staining was used to count the number of macrophages. Kaplan-Meier curves were used to analyze overall survival. The results indicated that the wall of deep-brain abscesses was thicker than that of superficial abscesses. There was a difference in the extent of macrophage infiltration of deep- and superficial-brain abscess walls, and differences in the extent of macrophage infiltration in the wall of brain abscesses caused by various microorganisms were statistically significant. Of note, among the brain abscesses caused by

Indexed as

abscess walldeep braininfectionmacrophage

Identifiers

PMID34447473
PMCPMC8355639
OpenAlexW3186399068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.