Evidence map›Paper›PMID 34447421›Full record

ArticleAfrican health sciences2021

Predictors of antiretroviral therapy interruptions and factors influencing return to care at the Nkolndongo Health District, Cameroon.

Marius Nsoh, Katayi E Tshimwanga, Busi A Ngum, Avelina Mgasa, Moses O Otieno, Bokwena Moali, Nathanael Sirili, Ndeso S Atanga, Gregory E Halle-Ekane

Abstract read
In one paragraph

Article in African health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Factors related to loss to follow-up among people living with HIV: a systematic review.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marius NsohDepartment of Public Health, School of Health Sciences, Catholic University of Central Africa; Cameroon.
Katayi E TshimwangaHIV Free Project, Cameroon Baptist Convention Health Services, Center region; Cameroon.
Busi A NgumWomen Health Program, Mbingo Baptist Hospital, Cameroon Baptist Convention Health Services; Cameroon.
Avelina MgasaMinistry of Health Community Development, Gender, Elderly and Children; National Blood Transfusion Service; Tanzania.
Moses O OtienoNational AIDS and Sexually Transmitted Infections Control Program (NASCOP); Kenya.
Bokwena MoaliMinistry of Health and Wellness, Okavango District, Botswana.
Nathanael SiriliDepartment of Development Studies, Muhimbili University of Health and Allied Sciences; Tanzania.
Ndeso S AtangaDepartment of Public Health, Obstetrics and Gynecology, Faculty of Health Sciences, University of Buea; Cameroon.
Gregory E Halle-EkaneDepartment of Public Health, Obstetrics and Gynecology, Faculty of Health Sciences, University of Buea; Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy is a lifelong commitment that requires consistent intake of tablets to optimize health outcomes, attain and maintain viral suppression.

objectiveWe aimed to elicit predictors of treatment interruption amongst PLHIV and identify motivating factors influencing return to care.

methodWe conducted a cross-sectional study using a mixed-method approach in four hospitals in Yaoundé. Sociodemographic and clinical data were collected from ART registers. Using purposeful sampling, thirteen participants were enrolled for interviews. Quantitative data were analyzed using Epi-Info and Atlas-TI for qualitative analysis. Ethical clearance approved by CBCHS-IRB.

resultsA total of 271 participants records were assessed. The mean age was 33 years (SD±11years). Private facilities CASS and CMNB registered respectively 53 (19.6%) and 14 (5.2%) participants while CMA Nkomo and IPC had 114 (42.1%) and 90 (33.2%) participants. Most participants (75.3%) were females [OR 1.14; CI 0.78-1.66] compare with males. 78% had no viral load test results. Transport cost and stigmatization constituted the most prominent predictors of treatment interruption (47.5%) and (10.5%) respectively. Belief in the discovery of an eminent HIV cure and the desire to raise offspring motivated 30% and 61%, respectively to resume treatment.

conclusionStructural barriers like exposed health facility, and dispensing ARVs in open spaces stigmatizes clients and increases odds of attrition. Attrition of patients on ART will be minimized through implementation of client centered approaches like multiplying proxy ART pick points, devolving stable clients to community ARV model.

Indexed as

Medication AdherenceAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCameroonCross-Sectional StudiesFemaleHIV InfectionsHumansInterviews as TopicMaleMiddle AgedMotivationQualitative ResearchAnti-HIV AgentsART interruptionattritionCameroonmotivating factorspredictorsreturn to care

Identifiers

PMID34447421
PMCPMC8367305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.