Evidence map›Paper›PMID 34447364›Full record

ArticleFrontiers in microbiology2021

Impact of Prior Infection on Severe Acute Respiratory Syndrome Coronavirus 2 Transmission in Syrian Hamsters.

Cheng Zhang, Zhendong Guo, Nan Li, Huan Cui, Keyin Meng, Lina Liu, Li Zhao, Shanshan Zhang, Chengfeng Qin, Juxiang Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Cheng ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Zhendong GuoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Nan LiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Huan CuiChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Keyin MengChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Lina LiuChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Li ZhaoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Shanshan ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Chengfeng QinBeijing Institute of Microbiology and Epidemiology, Beijing, China.
Juxiang LiuCollege of Veterinary Medicine, Hebei Agricultural University, Baoding, China.
Yuwei GaoChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Chunmao ZhangChangchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Hebei Agricultural University · CNChinese Academy of Agricultural Sciences · CNJilin University · CNInstitute of Microbiology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prior infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provides protective immunity against reinfection. However, whether prior infection blocks SARS-CoV-2 transmission is not yet clear. Here, we evaluated the impact of prior infection on SARS-CoV-2 transmission in Syrian hamsters. Our results showed that prior infection significantly reduced SARS-CoV-2 replication in Syrian hamsters, but sterilizing immunity was not achieved. Prior infection blocked the airborne transmission of SARS-CoV-2 from previously infected Syrian hamsters to naïve Syrian hamsters and previously infected Syrian hamsters. Moreover, prior infection substantially reduced the efficiency of direct contact transmission between previously infected Syrian hamsters. However, prior infection had limited impact on SARS-CoV-2 transmission from previously infected Syrian hamsters to naïve Syrian hamsters

Indexed as

airborne transmissioncontact transmissionprior infectionreinfectionsevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34447364
PMCPMC8383181
OpenAlexW3191538915

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.