Evidence map›Paper›PMID 34447304›Full record

ArticleFrontiers in pharmacology2021

Dose Dependent Antimicrobial Cellular Cytotoxicity-Implications for

Ana Copaescu, Phuti Choshi, Sarah Pedretti, Effie Mouhtouris, Jonathan Peter, Jason A Trubiano

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. The role of skin testing, drug challenge and IFN-γ ELISpot in delayed hypersensitivity to iodinated contrast media.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  4. Article
  5. Exploring cytokine outputs forThe World Allergy Organization journal · 2024
    Article
  6. Article
  7. Article
  8. Blister fluid as a cellular input forThe journal of allergy and clinical immunology. Global · 2022
    Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ana CopaescuCentre for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia.
Phuti ChoshiAllergy and Immunology Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
Sarah PedrettiAllergy and Immunology Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
Effie MouhtourisCentre for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia.
Jonathan PeterAllergy and Immunology Unit, University of Cape Town Lung Institute, Cape Town, South Africa.
Jason A TrubianoCentre for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, VIC, Australia.
Austin Health · AUUniversity of Cape Town · ZAPeter MacCallum Cancer Centre · AUSouth African Tuberculosis Vaccine Initiative · ZA

Funding

HIV-associated Tuberculosis Training Program (HATTP)D43TW010559 · FIC · UNIVERSITY OF CAPE TOWN · PI Graeme Ayton Meintjes · 2017 to 2026
$3.0M
Immune-mediated adverse drug reactions to HIV and TB treatments in South Africa: predict, prevent and improve long-term outcomes (IMARI SA study)R01AI152183 · NIAID · UNIVERSITY OF CAPE TOWN · PI MEINTJES, GRAEME AYTON, PHILLIPS, ELIZABETH · 2020 to 2025
$1.6M
IMmune-mediated Adverse drug Reactions In African HIV endemic setting (IMARI-SA study)K43TW011178 · FIC · UNIVERSITY OF CAPE TOWN LUNG INSTITUTE · PI PETER, JONATHAN · 2018 to 2022
$648k
FIC NIH HHS D43 TW010559FIC NIH HHS K43 TW011178NIAID NIH HHS R01 AI152183
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cytotoxicitydelayed hypersensitivity reactiondrug allergyenzyme linked ImmunoSpotflow cytometrylactate dehydrogenasesevere cutaneous adverse reactionT-cell

Identifiers

PMID34447304
PMCPMC8383281
OpenAlexW3191713454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.