Evidence map›Paper›PMID 34446953›Full record

ArticleIndian journal of dermatology

Correlation of Serum 25-Hydroxy Vitamin D and Interleukin-17 Levels with Disease Severity in Acne Vulgaris.

Ajeet Singh, Ananta Khurana, Kabir Sardana, Niharika Dixit, Anubhuti Chitkara

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Vitamin D in the Prevention and Treatment of Inflammatory Skin Diseases.International journal of molecular sciences · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ajeet SinghDepartment of Dermatology and Biochemistry, PGIMER and Dr. Ram Manohar Lohia Hospital New Delhi, Delhi, India.
Ananta KhuranaDepartment of Dermatology and Biochemistry, PGIMER and Dr. Ram Manohar Lohia Hospital New Delhi, Delhi, India.
Kabir SardanaDepartment of Dermatology and Biochemistry, PGIMER and Dr. Ram Manohar Lohia Hospital New Delhi, Delhi, India.
Niharika DixitDepartment of Dermatology and Biochemistry, PGIMER and Dr. Ram Manohar Lohia Hospital New Delhi, Delhi, India.
Anubhuti ChitkaraDepartment of Dermatology and Biochemistry, PGIMER and Dr. Ram Manohar Lohia Hospital New Delhi, Delhi, India.
Post Graduate Institute of Medical Education and Research · INAtal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association of Vitamin D (vit.D) and Interleukin 17 (IL-17) with acne vulgaris is uncertain in spite of induction of IL-17 by

methodsThe study included 50 patients of acne and 30 healthy controls. Serum 25(OH) D and IL-17 levels were measured using chemiluminescence immunoassay (CLIA) and enzyme-linked immunosorbent assay (ELISA), respectively.

resultsVitamin D deficiency was detected in 28% of patients with acne but only in 6.7% of the healthy controls (

conclusionsRaised IL-17 levels in acne correlate negatively with vit.D deficiency and both are significantly more prevalent in patients with acne as compared to healthy controls.

Indexed as

Acne vulgarisinterleukin-17vitamin D

Identifiers

PMID34446953
PMCPMC8375544
OpenAlexW3186531656

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.