Evidence map›Paper›PMID 34446951›Full record

ArticleIndian journal of dermatology

Fragrance, Sunscreens, Botanicals, and Potential Allergens in Bestseller 'Fairness' Creams in the Indian Market: A Consumer Exposure Study.

Hima Gopinath, Bodicharla Manjula, Kaliaperumal Karthikeyan

Open access · diamondAbstract read
In one paragraph

Article in Indian journal of dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Health Implications of Colorism: A Narrative Review of the Literature.Journal of racial and ethnic health disparities · 2026
    Review
  2. Content analysis of fairness product posts on Instagram.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hima GopinathDepartment of Dermatology, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.
Bodicharla ManjulaDepartment of Dermatology, Sri Manakula Vinayagar Medical College and Hospital, Pondicherry, India.
Kaliaperumal KarthikeyanDepartment of Dermatology, All India Institute of Medical Sciences, Mangalagiri, Guntur District, Andhra Pradesh, India.
Sri Manakula Vinayagar Medical College and Hospital · INAll India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe skin lightening industry has seen exponential growth in India. Consumers often present to the dermatologist with adverse cutaneous reactions to these 'fairness' (skin lightening) creams. The composition of these creams has not received sufficient attention.

objectiveTo identify fragrance, sunscreens, botanicals and potential allergens in the bestseller 'fairness' creams available in the Indian market.

methodsTwenty fairness (or whitening or lightening) creams were selected based on the 'bestseller' creams of one of the largest electronic commerce websites in India, and availability in local stores and unlabelled brands were excluded. Fragrance, sunscreens, botanicals and potential allergens were identified from the ingredient labels.

resultsTwenty bestseller fairness creams were included. The number of the listed ingredients in the fairness creams ranged from 6 to 49 (mean = 32.2). The most frequently listed ingredients included water, fragrance or parfum, glycerin, tocopherol/tocopherylacetate and titanium dioxide. Hydroquinone, monobenzyl hydroquinone, corticosteroids, tretinoin and mercury were not listed in any of the creams. Unspecified fragrance was listed in 19 (95%) creams and linalool (8,40%) was the most frequent specified fragrance. Titanium dioxide (14, 70 %) was the most common inorganic sunscreen and ethylhexyl methoxycinnamate (12 creams or 60% of creams) was the most common organic sunscreen. Twenty-seven botanicals were identified. Eight ingredients were potential allergens according to the Indian Cosmetic and Fragrance Series. The cost of the creams ranged from 95 to 1,095 in Indian rupees (mean 300.5).

conclusionsConsumers are exposed to a vast range of compounds in the quest for a lighter skin tone. Several potential allergens, particularly fragrance allergens, are present in addition to the eight allergens that were identified with the Indian Cosmetic and Fragrance Series. Increased awareness of the composition of skin lightening creams available in the market and strict regulation of these creams is needed.

Indexed as

Contact dermatitiscosmeticcosmetic dermatologycosmetic ingredients

Identifiers

PMID34446951
PMCPMC8375543
OpenAlexW3183651651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.