Evidence map›Paper›PMID 34446827›Full record

ArticleCommunications biology2021

Redox nanomedicine ameliorates chronic kidney disease (CKD) by mitochondrial reconditioning in mice.

Aniruddha Adhikari, Susmita Mondal, Tanima Chatterjee, Monojit Das, Pritam Biswas, Ria Ghosh, Soumendra Darbar, Hussain Alessa, Jalal T Althakafy, Ali Sayqal and 4 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Antibody-Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  5. Nanotherapeutics in Kidney Disease: Innovations, Challenges, and Future Directions.Journal of the American Society of Nephrology : JASN · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Chitosan functionalized MnCommunications biology · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Current Strategies and Potential Prospects for Nanoparticle-Mediated Treatment of Diabetic Nephropathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 3 countries.

Aniruddha AdhikariDepartment of Chemical, Biological and Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Kolkata, India.ORCID 0000-0001-6470-4099
Susmita MondalDepartment of Chemical, Biological and Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Kolkata, India.
Tanima ChatterjeeDepartment of Biochemistry, University of Calcutta, Kolkata, India.
Monojit DasDepartment of Zoology, Uluberia College, University of Calcutta, Uluberia, Howrah, India.
Pritam BiswasDepartment of Microbiology, St. Xavier's College, Kolkata, India.
Ria GhoshDepartment of Biochemistry, University of Calcutta, Kolkata, India.
Soumendra DarbarResearch & Development Division, Dey's Medical Stores (Mfg.) Ltd, Kolkata, India.
Hussain AlessaDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Jalal T AlthakafyDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Ali SayqalDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Saleh A AhmedDepartment of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Anjan Kumar DasDepartment of Pathology, Calcutta National Medical College and Hospital, Kolkata, India.
Maitree BhattacharyyaDepartment of Biochemistry, University of Calcutta, Kolkata, India.
Samir Kumar PalDepartment of Chemical, Biological and Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Kolkata, India. skpal@bose.res.in.ORCID 0000-0001-6943-5828
University of Calcutta · INUmm al-Qura University · SAS.N. Bose National Centre for Basic Sciences · INCalcutta National Medical College and Hospital · INMedical College and Hospital, Kolkata · INSt. Xavier's College (Autonomous)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting reactive oxygen species (ROS) while maintaining cellular redox signaling is crucial in the development of redox medicine as the origin of several prevailing diseases including chronic kidney disease (CKD) is linked to ROS imbalance and associated mitochondrial dysfunction. Here, we have shown that a potential nanomedicine comprising of Mn

Indexed as

NanomedicineAnimalsFemaleMaleMiceMitochondriaOxidation-ReductionReactive Oxygen SpeciesRenal Insufficiency, ChronicReactive Oxygen Species

Identifiers

PMID34446827
PMCPMC8390471
OpenAlexW3194945167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.